Pancytopenia in a patient with rheumatoid arthritis on low-dose methotrexate

M. P. Iqbal, A. A. Ali, A. Iqbal, M. A. Hussain

Research output: Contribution to journalArticlepeer-review


We report a case of pancytopenia in an elderly rheumatoid arthritis patient in which use of methotrexate (MTX) in very low dose (10mg/week), had led to accumulation of appreciable quantity of MTX in serum leading to bone marrow suppression. Immediate withdrawal of MTX and folate supplementation however led to a significant improvement of blood picture.

Original languageEnglish
Pages (from-to)430-431
Number of pages2
JournalJournal of the College of Physicians and Surgeons--Pakistan : JCPSP
Issue number9
Publication statusPublished - 1999


  • Methotrexate
  • Pancytopenia
  • Rheumatoid arthritis


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