Pancytopenia in a patient with rheumatoid arthritis on low-dose methotrexate

M. P. Iqbal; A. A. Ali; A. Iqbal; M. A. Hussain

Pancytopenia in a patient with rheumatoid arthritis on low-dose methotrexate

M. P. Iqbal, A. A. Ali, A. Iqbal, M. A. Hussain

Department of Biological & Biomedical Sciences, Medical College, Pakistan

Research output: Contribution to journal › Article › peer-review

Abstract

We report a case of pancytopenia in an elderly rheumatoid arthritis patient in which use of methotrexate (MTX) in very low dose (10mg/week), had led to accumulation of appreciable quantity of MTX in serum leading to bone marrow suppression. Immediate withdrawal of MTX and folate supplementation however led to a significant improvement of blood picture.

Original language	English
Pages (from-to)	430-431
Number of pages	2
Journal	Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Volume	9
Issue number	9
Publication status	Published - 1999

Keywords

Methotrexate
Pancytopenia
Rheumatoid arthritis

Cite this

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abstract = "We report a case of pancytopenia in an elderly rheumatoid arthritis patient in which use of methotrexate (MTX) in very low dose (10mg/week), had led to accumulation of appreciable quantity of MTX in serum leading to bone marrow suppression. Immediate withdrawal of MTX and folate supplementation however led to a significant improvement of blood picture.",

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AB - We report a case of pancytopenia in an elderly rheumatoid arthritis patient in which use of methotrexate (MTX) in very low dose (10mg/week), had led to accumulation of appreciable quantity of MTX in serum leading to bone marrow suppression. Immediate withdrawal of MTX and folate supplementation however led to a significant improvement of blood picture.

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Pancytopenia in a patient with rheumatoid arthritis on low-dose methotrexate

Abstract

Keywords

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