Phosphorescent Ir (III) complexes as cellular staining agents for biomedical molecular imaging

Sana Shaikh; Yihan Wang; Fawad ur Rehman; Hui Jiang; Xuemei Wang

doi:10.1016/j.ccr.2020.213344

Phosphorescent Ir (III) complexes as cellular staining agents for biomedical molecular imaging

Sana Shaikh
, Yihan Wang
, Fawad ur Rehman
, Hui Jiang
, Xuemei Wang

Research output: Contribution to journal › Review article › peer-review

73 Citations (Scopus)

Abstract

Phosphorescent Ir(III) complexes have attracted abundant attention in biomedical research due to their wide ranging properties and organelle specific intracellular imaging. Various types of Ir (III) complexes have been synthesized for visualization and monitoring of subcellular organelles and diagnosis of cancer. The aim of this review is to evaluate the progress of the phosphorescent Ir(III) complexes in bioimaging applications. We intend to highlight the use of Ir(III) complexes for staining the subcellular organelles, providing phosphorescence lifetime imaging microscopy, two photon and hypoxic tumor bioimaging.

Original language	English (UK)
Article number	213344
Journal	Coordination Chemistry Reviews
Volume	416
DOIs	https://doi.org/10.1016/j.ccr.2020.213344
Publication status	Published - 1 Aug 2020
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Bioimaging
Cellular functionalities
Ir (III) complexes
Phosphorescence

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10.1016/j.ccr.2020.213344

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title = "Phosphorescent Ir (III) complexes as cellular staining agents for biomedical molecular imaging",

abstract = "Phosphorescent Ir(III) complexes have attracted abundant attention in biomedical research due to their wide ranging properties and organelle specific intracellular imaging. Various types of Ir (III) complexes have been synthesized for visualization and monitoring of subcellular organelles and diagnosis of cancer. The aim of this review is to evaluate the progress of the phosphorescent Ir(III) complexes in bioimaging applications. We intend to highlight the use of Ir(III) complexes for staining the subcellular organelles, providing phosphorescence lifetime imaging microscopy, two photon and hypoxic tumor bioimaging.",

keywords = "Bioimaging, Cellular functionalities, Ir (III) complexes, Phosphorescence",

author = "Sana Shaikh and Yihan Wang and \{ur Rehman\}, Fawad and Hui Jiang and Xuemei Wang",

note = "Publisher Copyright: {\textcopyright} 2020",

year = "2020",

month = aug,

day = "1",

doi = "10.1016/j.ccr.2020.213344",

language = "English (UK)",

volume = "416",

journal = "Coordination Chemistry Reviews",

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TY - JOUR

T1 - Phosphorescent Ir (III) complexes as cellular staining agents for biomedical molecular imaging

AU - Shaikh, Sana

AU - Wang, Yihan

AU - ur Rehman, Fawad

AU - Jiang, Hui

AU - Wang, Xuemei

PY - 2020/8/1

Y1 - 2020/8/1

N2 - Phosphorescent Ir(III) complexes have attracted abundant attention in biomedical research due to their wide ranging properties and organelle specific intracellular imaging. Various types of Ir (III) complexes have been synthesized for visualization and monitoring of subcellular organelles and diagnosis of cancer. The aim of this review is to evaluate the progress of the phosphorescent Ir(III) complexes in bioimaging applications. We intend to highlight the use of Ir(III) complexes for staining the subcellular organelles, providing phosphorescence lifetime imaging microscopy, two photon and hypoxic tumor bioimaging.

AB - Phosphorescent Ir(III) complexes have attracted abundant attention in biomedical research due to their wide ranging properties and organelle specific intracellular imaging. Various types of Ir (III) complexes have been synthesized for visualization and monitoring of subcellular organelles and diagnosis of cancer. The aim of this review is to evaluate the progress of the phosphorescent Ir(III) complexes in bioimaging applications. We intend to highlight the use of Ir(III) complexes for staining the subcellular organelles, providing phosphorescence lifetime imaging microscopy, two photon and hypoxic tumor bioimaging.

KW - Bioimaging

KW - Cellular functionalities

KW - Ir (III) complexes

KW - Phosphorescence

UR - https://www.scopus.com/pages/publications/85083394493

U2 - 10.1016/j.ccr.2020.213344

DO - 10.1016/j.ccr.2020.213344

M3 - Review article

AN - SCOPUS:85083394493

SN - 0010-8545

VL - 416

JO - Coordination Chemistry Reviews

JF - Coordination Chemistry Reviews

M1 - 213344

ER -

Phosphorescent Ir (III) complexes as cellular staining agents for biomedical molecular imaging

Abstract

UN SDGs

Keywords

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