Photodynamic Therapy in Adult Intra-axial Brain Tumours

Zanib Javed; Hafiza Fatima Aziz; Muhammad Shahzad Shamim

doi:10.47391/JPMA.24-11

Photodynamic Therapy in Adult Intra-axial Brain Tumours

Zanib Javed, Hafiza Fatima Aziz, Muhammad Shahzad Shamim

Section of Neurosurgery, Department of Surgery, Medical College, Pakistan

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

The management of high-grade gliomas is challenging considering their infiltrative nature, involvement of the eloquent cortex, and high recurrence rate. Photodynamic therapy (PDT) is an emerging modality that selectively destroys tumour cells while preserving normal brain tissue. Its safety, and the concurrent use with surgery, radiation, and chemotherapy, is some of its appealing tenets. Here, we present a review of the literature regarding the mechanism, safety, and efficacy of PDT.

Original language	English (US)
Pages (from-to)	404-406
Number of pages	3
Journal	Journal of the Pakistan Medical Association
Volume	74
Issue number	2
DOIs	https://doi.org/10.47391/JPMA.24-11
Publication status	Published - Feb 2024

Keywords

adjuvant treatment
brain tumour
glioma

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10.47391/JPMA.24-11

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abstract = "The management of high-grade gliomas is challenging considering their infiltrative nature, involvement of the eloquent cortex, and high recurrence rate. Photodynamic therapy (PDT) is an emerging modality that selectively destroys tumour cells while preserving normal brain tissue. Its safety, and the concurrent use with surgery, radiation, and chemotherapy, is some of its appealing tenets. Here, we present a review of the literature regarding the mechanism, safety, and efficacy of PDT.",

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AB - The management of high-grade gliomas is challenging considering their infiltrative nature, involvement of the eloquent cortex, and high recurrence rate. Photodynamic therapy (PDT) is an emerging modality that selectively destroys tumour cells while preserving normal brain tissue. Its safety, and the concurrent use with surgery, radiation, and chemotherapy, is some of its appealing tenets. Here, we present a review of the literature regarding the mechanism, safety, and efficacy of PDT.

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KW - glioma

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Photodynamic Therapy in Adult Intra-axial Brain Tumours

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Keywords

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