Pleomorphic liposarcoma of chest wall: a rare entity with challenging management

Pleomorphic liposarcoma is the rarest subtype of liposarcoma, with a high recurrence rate and poor prognosis. We present the case of young man with a rapidly growing large anterior chest wall liposarcoma that was excised, but he suffered 3 local recurrences in one year, showing the aggressive nature of the disease. If not completely resected with a tumor-free margin, the patient may have to endure multiple extensive surgeries in quick succession, increasing the chances of metastasis and a fatal outcome. Pleomorphic liposarcoma should be radically excised along with radiotherapy and strict follow-up of such patients.