Polycystic ovary syndrome, subfertility and Vitamin D deficiency

Arfa Azhar, Fatima Abid, Rehana Rehman

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


Polycystic ovarian syndrome (PCOS) is the most common endocrine female disorder, affecting 4-18% women of reproductive age. The prevalence of PCOS in South Asian women, especially in Pakistani women, is much higher (52%) as compared to white population (20 - 25% in UK). In Pakistan, vitamin D status displays 31.2% vitamin D insufficiency, 53.5% vitamin D deficiency, and 15.3% normal vitamin D values. Vitamin D deficiency, though very common in the general population, is even more prevalent in PCOS patients, seen in approximately 67-85%, which further correlates to their related comorbidities. A lot of researches have to be directed to examine the association among the PCOS and vitamin D, which may display monitoring role in several symptoms related to PCOS, such as ovulatory dysfunction, endocrine disruption, and insulin resistance. Vitamin D supplementation can, therefore, be employed to improve the metabolic and endocrine disorders; especially improving hormonal profile, oxidative stress, and ovulation outcome in PCOS patients.

Original languageEnglish
Pages (from-to)545-546
Number of pages2
JournalJournal of the College of Physicians and Surgeons--Pakistan : JCPSP
Issue number5
Publication statusPublished - 1 May 2020


  • Infertility
  • Insulin Resistance
  • Ovulatory Dysfunction
  • Vitamin D


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