Polymorphic status of PRKAA2 gene in Pakistani buffaloes

Waqas Ahmad Khan; Tanveer Hussain; Masroor Ellahi Babar; Asif Nadeem; Ali Raza Awan; Ambrin Fatima; Rashid Saif

doi:10.17957/IJAB/15.0149

Polymorphic status of PRKAA2 gene in Pakistani buffaloes

Waqas Ahmad Khan, Tanveer Hussain, Masroor Ellahi Babar, Asif Nadeem, Ali Raza Awan, Ambrin Fatima, Rashid Saif

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

This study was designed to find single nucleotide polymorphism (SNPs) in coding and non-coding region of PRKAA2 gene in Nili-Ravi and Kundi buffaloes. The PRKAA2 gene (AMPKα2) of 100 animals from both buffalo breeds were sequenced for SNPs identification. A total number of 43 inter and intra-generic SNPs were found. Out of which 17 SNPs were detected among buffalo breeds (intra-generic). All SNPs were intronic and may have a role in gene regulation and splicing patterns. These SNPs might be associated with commercially important production traits. This is the first study to identify novel SNPs that are linked to energy metabolism and production traits of buffalo.

Original language	English
Pages (from-to)	903-905
Number of pages	3
Journal	International Journal of Agriculture and Biology
Volume	18
Issue number	5
DOIs	https://doi.org/10.17957/IJAB/15.0149
Publication status	Published - 2016
Externally published	Yes

Keywords

AMPK
Buffalo
PRKAA2
Pakistan
SNP

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10.17957/IJAB/15.0149

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title = "Polymorphic status of PRKAA2 gene in Pakistani buffaloes",

abstract = "This study was designed to find single nucleotide polymorphism (SNPs) in coding and non-coding region of PRKAA2 gene in Nili-Ravi and Kundi buffaloes. The PRKAA2 gene (AMPKα2) of 100 animals from both buffalo breeds were sequenced for SNPs identification. A total number of 43 inter and intra-generic SNPs were found. Out of which 17 SNPs were detected among buffalo breeds (intra-generic). All SNPs were intronic and may have a role in gene regulation and splicing patterns. These SNPs might be associated with commercially important production traits. This is the first study to identify novel SNPs that are linked to energy metabolism and production traits of buffalo.",

keywords = "AMPK, Buffalo, PRKAA2, Pakistan, SNP",

author = "Khan, {Waqas Ahmad} and Tanveer Hussain and Babar, {Masroor Ellahi} and Asif Nadeem and Awan, {Ali Raza} and Ambrin Fatima and Rashid Saif",

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language = "English",

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TY - JOUR

T1 - Polymorphic status of PRKAA2 gene in Pakistani buffaloes

AU - Khan, Waqas Ahmad

AU - Hussain, Tanveer

AU - Babar, Masroor Ellahi

AU - Nadeem, Asif

AU - Awan, Ali Raza

AU - Fatima, Ambrin

AU - Saif, Rashid

PY - 2016

Y1 - 2016

N2 - This study was designed to find single nucleotide polymorphism (SNPs) in coding and non-coding region of PRKAA2 gene in Nili-Ravi and Kundi buffaloes. The PRKAA2 gene (AMPKα2) of 100 animals from both buffalo breeds were sequenced for SNPs identification. A total number of 43 inter and intra-generic SNPs were found. Out of which 17 SNPs were detected among buffalo breeds (intra-generic). All SNPs were intronic and may have a role in gene regulation and splicing patterns. These SNPs might be associated with commercially important production traits. This is the first study to identify novel SNPs that are linked to energy metabolism and production traits of buffalo.

AB - This study was designed to find single nucleotide polymorphism (SNPs) in coding and non-coding region of PRKAA2 gene in Nili-Ravi and Kundi buffaloes. The PRKAA2 gene (AMPKα2) of 100 animals from both buffalo breeds were sequenced for SNPs identification. A total number of 43 inter and intra-generic SNPs were found. Out of which 17 SNPs were detected among buffalo breeds (intra-generic). All SNPs were intronic and may have a role in gene regulation and splicing patterns. These SNPs might be associated with commercially important production traits. This is the first study to identify novel SNPs that are linked to energy metabolism and production traits of buffalo.

KW - AMPK

KW - Buffalo

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KW - SNP

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DO - 10.17957/IJAB/15.0149

M3 - Article

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EP - 905

JO - International Journal of Agriculture and Biology

JF - International Journal of Agriculture and Biology

IS - 5

ER -

Polymorphic status of PRKAA2 gene in Pakistani buffaloes

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Keywords

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