TY - JOUR
T1 - Population attributable fractions of clinical and social risk factors for suicide in Bangladesh
T2 - Finding from a case–control psychological autopsy study
AU - Arafat, S. M.Yasir
AU - Khan, Md Abdullah Saeed
AU - Knipe, Duleeka
AU - Khan, Murad M.
N1 - Funding Information:
Duleeka Knipe was supported by the Wellcome Trust through an Institutional Strategic Support Fund Award to the University of Bristol [204813] and the Elizabeth Blackwell Institute for Health Research, University of Bristol.
Publisher Copyright:
© 2021 The Authors. Brain and Behavior published by Wiley Periodicals LLC
PY - 2021/12
Y1 - 2021/12
N2 - Background: Our knowledge of suicide in low-income countries is limited. Understanding the importance of factors that contribute to suicide risk will allow for the appropriate allocation of limited resources. In order to prioritize suicide prevention activities in Bangladesh, we estimate the fractions of suicides attributable to key risk factors. Methods: Using data from matched cases (100) and controls (100) as part of a psychological autopsy study in Dhaka, we estimate the population attributable fraction for key clinical (psychiatric disorders and physical disability), and social (life events, psychical and/or sexual abuse, unemployment, and social isolation) risk factors for suicide in Bangladesh. Results: Assuming a causal relationship, life events were responsible for the largest proportion of suicide deaths (85.9%; confidence interval [CI], 79.6–90.2), followed by mental disorder (49.5%; CI, 45.3–53.4). The population attributable fraction for the risk factors was 42.9% (CI, 40.6–45) for depression, 11% (CI, 8.9–13) for sexual abuse, and 34.9% (CI, 10.1–52.9) for social isolation. Conclusions: The study determined the population attributable fraction of risk factors for suicide in Bangladesh. Prevention strategies should be prioritized on the management of the aftermaths of adverse life events, treatment of psychiatric disorders, sexual abuse, and social isolation in the country.
AB - Background: Our knowledge of suicide in low-income countries is limited. Understanding the importance of factors that contribute to suicide risk will allow for the appropriate allocation of limited resources. In order to prioritize suicide prevention activities in Bangladesh, we estimate the fractions of suicides attributable to key risk factors. Methods: Using data from matched cases (100) and controls (100) as part of a psychological autopsy study in Dhaka, we estimate the population attributable fraction for key clinical (psychiatric disorders and physical disability), and social (life events, psychical and/or sexual abuse, unemployment, and social isolation) risk factors for suicide in Bangladesh. Results: Assuming a causal relationship, life events were responsible for the largest proportion of suicide deaths (85.9%; confidence interval [CI], 79.6–90.2), followed by mental disorder (49.5%; CI, 45.3–53.4). The population attributable fraction for the risk factors was 42.9% (CI, 40.6–45) for depression, 11% (CI, 8.9–13) for sexual abuse, and 34.9% (CI, 10.1–52.9) for social isolation. Conclusions: The study determined the population attributable fraction of risk factors for suicide in Bangladesh. Prevention strategies should be prioritized on the management of the aftermaths of adverse life events, treatment of psychiatric disorders, sexual abuse, and social isolation in the country.
KW - case–control study
KW - population attributable fraction
KW - psychological autopsy
KW - risk factors
KW - suicide in Bangladesh
UR - http://www.scopus.com/inward/record.url?scp=85118863973&partnerID=8YFLogxK
U2 - 10.1002/brb3.2409
DO - 10.1002/brb3.2409
M3 - Article
C2 - 34758201
AN - SCOPUS:85118863973
SN - 2157-9032
VL - 11
JO - Brain and Behavior
JF - Brain and Behavior
IS - 12
M1 - e2409
ER -