Post-transfusion hypertension, convulsion and intracranial haemorrhage in β-thalassemia major

Syed Asif Masood, Anita Zaidi

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5 Citations (Scopus)


The haematologic disorder β-thalassemia major is common in Pakistan. We describe a patient with undiagnosed thalassemia presenting with hypertension and convulsions and found to have cerebral haemorrhage on neuro-imaging. He had been transfused 2 weeks before this illness. Our experience is similar to a few case reports described in literature that were found to have cerebral haemorrhages post-mortem after a similar clinical presentation. All patients had a blood transfusion within 2 weeks prior to the presentation so association with transfusion has been proposed. We have reviewed the several mechanisms presented and discussed the findings.

Original languageEnglish
Pages (from-to)473-475
Number of pages3
JournalJournal of the College of Physicians and Surgeons--Pakistan : JCPSP
Issue number7
Publication statusPublished - Jul 2012


  • Blood transfusion
  • Convulsion
  • Haemorrhage
  • Hypertension
  • Intracranial
  • Thalassemia


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