TY - JOUR
T1 - Predictors of Preterm Neonatal Mortality in India and Pakistan
T2 - A Secondary Analysis of Data from PURPOSe Study
AU - Tikmani, Shiyam Sunder
AU - Saleem, Sarah
AU - Sadia, Afreen
AU - M. Bann, Carla
AU - Bozdar, Muhammad Hayat
AU - Raza, Jamal
AU - Dhaded, Sangappa M.
AU - Goudar, Shivaprasad S.
AU - Gowdar, Guruparasad
AU - Yasmin, Haleema
AU - McClure, Elizabeth M.
AU - Goldenberg, Robert L.
N1 - Publisher Copyright:
© The Author(s) 2024.
PY - 2024/1/1
Y1 - 2024/1/1
N2 - Objective. To create a prediction model for preterm neonatal mortality. Methods. A secondary analysis was conducted using data from a prospective cohort study, the Project to Understand and Research Preterm Pregnancy Outcome South Asia. The Cox proportional hazard model was used and adjusted hazard ratios (AHR) with 95% confidence intervals (95% CI) were reported. Results. Overall, 3446 preterm neonates were included. The mean age of preterm neonates was 0.65 (1.25) hours and 52% were female. The preterm neonatal mortality rate was 23.3%. The maternal factors predicting preterm neonatal death was any antepartum hemorrhage, AHR 1.99 (1.60-2.47), while neonatal predictors were preterm who received positive pressure ventilation AHR 1.30 (1.08-1.57), temperature <35.5°C AHR 1.18 (1.00-1.39), and congenital malformations AHR 3.31 (2.64-4.16). Conclusion. This study identified key maternal and neonatal predictors of preterm neonatal mortality, emphasizing the need for targeted interventions and collaborative public health efforts to address disparities and regional variations.
AB - Objective. To create a prediction model for preterm neonatal mortality. Methods. A secondary analysis was conducted using data from a prospective cohort study, the Project to Understand and Research Preterm Pregnancy Outcome South Asia. The Cox proportional hazard model was used and adjusted hazard ratios (AHR) with 95% confidence intervals (95% CI) were reported. Results. Overall, 3446 preterm neonates were included. The mean age of preterm neonates was 0.65 (1.25) hours and 52% were female. The preterm neonatal mortality rate was 23.3%. The maternal factors predicting preterm neonatal death was any antepartum hemorrhage, AHR 1.99 (1.60-2.47), while neonatal predictors were preterm who received positive pressure ventilation AHR 1.30 (1.08-1.57), temperature <35.5°C AHR 1.18 (1.00-1.39), and congenital malformations AHR 3.31 (2.64-4.16). Conclusion. This study identified key maternal and neonatal predictors of preterm neonatal mortality, emphasizing the need for targeted interventions and collaborative public health efforts to address disparities and regional variations.
KW - India
KW - Pakistan
KW - predictors
KW - preterm neonatal mortality
KW - preterm neonates
UR - http://www.scopus.com/inward/record.url?scp=85187871382&partnerID=8YFLogxK
U2 - 10.1177/2333794X241236617
DO - 10.1177/2333794X241236617
M3 - Article
AN - SCOPUS:85187871382
SN - 2333-794X
VL - 11
JO - Global Pediatric Health
JF - Global Pediatric Health
ER -
