Preparation of 188Re-lanreotide peptide and its quality control

A. Mushtaq, Shahid Pervez, I. Haider

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


A simple method is described for the preparation of 188Re-Lanreotide, a radiolabeled synthetic peptide derived from an analogue of somatostatin, using Lanreotide (50 µg) and stannous tartrate to which is added carrier-free 188Re. The radiolabeling has been carried out with ∼555 MBq (15 mCi) with a >95% labeling efficiency and no need for subsequent purification. ITLC and HPLC techniques were employed for monitoring the stability and labeling yield. Radiolabeling results in one major peak when analyzed by reverse-phase (RP) HPLC.

Original languageEnglish
Pages (from-to)495-498
Number of pages4
JournalRadiochimica Acta
Issue number36739
Publication statusPublished - 2000
Externally publishedYes


  • Direct labeling
  • Lanreotide
  • Rhenium-188
  • Somatostatin analog
  • Transchelating agent


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