Prescribing Patterns of Antihypertensive Medications in Low- and Middle-Income Countries: A Systematic Review

Verda Arshad, Zainab Samad, Jai Das, Aysha Almas, Nouman Rashid, Salim S. Virani, Gerald S. Bloomfield, Tazeen H. Jafar, Bilal Ahmed

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Hypertension is highly prevalent, but its pharmacological management has not been well evaluated in low- and middle-income countries (LMICs). This review examined the prescribing patterns of antihypertensives in LMICs. Data were extracted from a total of 26 studies spanning the time period 2000 to 2018. In 10 studies, calcium channel blockers (CCBs) were the most frequently prescribed medication for managing hypertension (range = 33% to 72%); in six studies, renin angiotensin system (RAS) blockers (range = 25% to 83%); in five studies, diuretics (range = 39% to 99%); and in five studies, β-blockers (BBs; range = 26% to 49%) were the most commonly prescribed antihypertensive medications. Prescribing sedatives and sublingual administration of captopril for controlling hypertension was also reported in 3 studies. Only 10 studies presented their findings in light of national or international guidelines. This review calls for further antihypertensive utilization and dispensation studies and a better understanding of clinician’s perception and practice of hypertension management guidelines in LMICs.

Original languageEnglish
Pages (from-to)14-22
Number of pages9
JournalAsia-Pacific Journal of Public Health
Volume33
Issue number1
DOIs
Publication statusPublished - Jan 2021

Keywords

  • antihypertensives
  • hypertension
  • low- and middle-income countries
  • prescribing patterns
  • systematic review

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