Primary adrenal leiomyosarcoma

Syed Muhammad Nazim; Muhammad Hummam Siddique; Imran Khan Jalbani; Ayesha Nusrat

doi:10.1136/bcr-2025-266476

Primary adrenal leiomyosarcoma

Syed Muhammad Nazim, Muhammad Hummam Siddique, Imran Khan Jalbani, Ayesha Nusrat

Section of Urology, Department of Surgery, Medical College, Pakistan

Research output: Contribution to journal › Article › peer-review

Abstract

Primary adrenal leiomyosarcoma is an extremely rare soft tissue tumour arising from the smooth muscle of adrenal vascular structures, with approximately 50 reported cases worldwide. The tumour typically presents with non-specific symptoms and does not produce hormones, often leading to a delayed diagnosis. It is usually identified on CT or MRI, but definitive diagnosis requires histopathology and immunohistochemistry. We describe the case of a young woman in her early 30s who presented with epigastric and left flank pain and was subsequently found to have a large adrenal mass. She underwent surgical resection and remains recurrence-free 13 months postsurgery.

Original language	English (US)
Article number	e266476
Journal	BMJ Case Reports
Volume	18
Issue number	10
DOIs	https://doi.org/10.1136/bcr-2025-266476
Publication status	Published - Oct 2025

Keywords

Adrenal disorders
Endocrine cancer
Incidence
Pathology
Urological cancer

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1136/bcr-2025-266476

Cite this

@article{e32bdeb1459c41e4a0b1fa09b9fcd1f4,

title = "Primary adrenal leiomyosarcoma",

abstract = "Primary adrenal leiomyosarcoma is an extremely rare soft tissue tumour arising from the smooth muscle of adrenal vascular structures, with approximately 50 reported cases worldwide. The tumour typically presents with non-specific symptoms and does not produce hormones, often leading to a delayed diagnosis. It is usually identified on CT or MRI, but definitive diagnosis requires histopathology and immunohistochemistry. We describe the case of a young woman in her early 30s who presented with epigastric and left flank pain and was subsequently found to have a large adrenal mass. She underwent surgical resection and remains recurrence-free 13 months postsurgery.",

keywords = "Adrenal disorders, Endocrine cancer, Incidence, Pathology, Urological cancer",

author = "Nazim, \{Syed Muhammad\} and Siddique, \{Muhammad Hummam\} and Jalbani, \{Imran Khan\} and Ayesha Nusrat",

note = "Publisher Copyright: {\textcopyright} BMJ Publishing Group Limited 2025. No commercial re-use. See rights and permissions. Published by BMJ Group.",

year = "2025",

month = oct,

doi = "10.1136/bcr-2025-266476",

language = "English (US)",

volume = "18",

journal = "BMJ Case Reports",

issn = "1757-790X",

publisher = "BMJ Publishing Group",

number = "10",

}

TY - JOUR

T1 - Primary adrenal leiomyosarcoma

AU - Nazim, Syed Muhammad

AU - Siddique, Muhammad Hummam

AU - Jalbani, Imran Khan

AU - Nusrat, Ayesha

N1 - Publisher Copyright: © BMJ Publishing Group Limited 2025. No commercial re-use. See rights and permissions. Published by BMJ Group.

PY - 2025/10

Y1 - 2025/10

N2 - Primary adrenal leiomyosarcoma is an extremely rare soft tissue tumour arising from the smooth muscle of adrenal vascular structures, with approximately 50 reported cases worldwide. The tumour typically presents with non-specific symptoms and does not produce hormones, often leading to a delayed diagnosis. It is usually identified on CT or MRI, but definitive diagnosis requires histopathology and immunohistochemistry. We describe the case of a young woman in her early 30s who presented with epigastric and left flank pain and was subsequently found to have a large adrenal mass. She underwent surgical resection and remains recurrence-free 13 months postsurgery.

AB - Primary adrenal leiomyosarcoma is an extremely rare soft tissue tumour arising from the smooth muscle of adrenal vascular structures, with approximately 50 reported cases worldwide. The tumour typically presents with non-specific symptoms and does not produce hormones, often leading to a delayed diagnosis. It is usually identified on CT or MRI, but definitive diagnosis requires histopathology and immunohistochemistry. We describe the case of a young woman in her early 30s who presented with epigastric and left flank pain and was subsequently found to have a large adrenal mass. She underwent surgical resection and remains recurrence-free 13 months postsurgery.

KW - Adrenal disorders

KW - Endocrine cancer

KW - Incidence

KW - Pathology

KW - Urological cancer

UR - https://www.scopus.com/pages/publications/105020268466

U2 - 10.1136/bcr-2025-266476

DO - 10.1136/bcr-2025-266476

M3 - Article

C2 - 41161768

AN - SCOPUS:105020268466

SN - 1757-790X

VL - 18

JO - BMJ Case Reports

JF - BMJ Case Reports

IS - 10

M1 - e266476

ER -

Primary adrenal leiomyosarcoma

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this