Priorities for cancer research in low- and middle-income countries: a global perspective

C. S. Pramesh, Rajendra A. Badwe, Nirmala Bhoo-Pathy, Christopher M. Booth, Girish Chinnaswamy, Anna J. Dare, Victor Piana de Andrade, David J. Hunter, Satish Gopal, Mary Gospodarowicz, Sanjeeva Gunasekera, Andre Ilbawi, Sharon Kapambwe, Peter Kingham, Tezer Kutluk, Nirmal Lamichhane, Miriam Mutebi, Jackson Orem, Groesbeck Parham, Priya RanganathanManju Sengar, Richard Sullivan, Soumya Swaminathan, Ian F. Tannock, Vivek Tomar, Verna Vanderpuye, Cherian Varghese, Elisabete Weiderpass

Research output: Contribution to journalArticlepeer-review

87 Citations (Scopus)


Cancer research currently is heavily skewed toward high-income countries (HICs), with little research conducted in, and relevant to, the problems of low- and middle-income countries (LMICs). This regional discordance in cancer knowledge generation and application needs to be rebalanced. Several gaps in the research enterprise of LMICs need to be addressed to promote regionally relevant research, and radical rethinking is needed to address the burning issues in cancer care in these regions. We identified five top priorities in cancer research in LMICs based on current and projected needs: reducing the burden of patients with advanced disease; improving access and affordability, and outcomes of cancer treatment; value-based care and health economics; quality improvement and implementation research; and leveraging technology to improve cancer control. LMICs have an excellent opportunity to address important questions in cancer research that could impact cancer control globally. Success will require collaboration and commitment from governments, policy makers, funding agencies, health care organizations and leaders, researchers and the public.

Original languageEnglish
Pages (from-to)649-657
Number of pages9
JournalNature Medicine
Issue number4
Publication statusPublished - Apr 2022


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