Prognostic Value of BRAF Mutation in Glioblastoma

Ayesha Sohail, Qurat Ul Ain Virani, Hafiza Fatima Aziz, Muhammad Shahzad Shamim

Research output: Contribution to journalArticlepeer-review

Abstract

With advances in molecular genetics, exploring targetable mutations for treating glioblastoma (GBM) patients, has become a centre of interest in modern day neuropathology. BRAF mutation has been extensively reported in several brain tumours. Recent studies report identification of BRAF mutation in GBM patients, especially isocitrate dehydrogenase wildtype glioblastomas (IDH-WT GBM), and its potential role in patient outcomes. Here we discuss the existing literature on the prognostic value of BRAF mutation in GBM.

Original languageEnglish
Pages (from-to)185-186
Number of pages2
JournalJournal of the Pakistan Medical Association
Volume74
Issue number1
DOIs
Publication statusPublished - Jan 2024

Keywords

  • BRAF mutation
  • Glioblastoma
  • prognosis

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