Protein associated with the sensory cell layer of the rainbow trout saccular macula

Dennis G. Drescher, Khalid M. Khan, Richard L. Arden, Marian J. Drescher, Thomas P. Kerr, James S. Hatfield

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


A protein has been detected that is associated with the saccular hair cell layer of the rainbow trout, Salmo gairdnerii R. By one-and two-dimensional SDS polyacrylamide gel electrophoresis, the molecular weight and isoelectric point of this protein are estimated to be 13.6 and 8.8 kDa, respectively. The 13.6 kDa protein cannot be detected electrophoretically in brain, gill, liver, and fractions containing the basal lamina, non-sensory epithelium, and saccular nerve. This protein does not bind antibodies to bovine myelin basic protein, while trout myelin basic proteins in the same molecular weight range do. In addition, the protein does not bind concanavalin A or react with the periodic acid-Schiff reagent. The 13.6 kDa band represents about 1% of the total protein in saccular sensory epithelium, and may be a marker protein for the hair cell layer.

Original languageEnglish
Pages (from-to)225-235
Number of pages11
JournalBrain Research
Issue number2
Publication statusPublished - 24 Apr 1989
Externally publishedYes


  • Electrophoresis
  • Hair cell
  • Marker protein
  • Saccular macula


Dive into the research topics of 'Protein associated with the sensory cell layer of the rainbow trout saccular macula'. Together they form a unique fingerprint.

Cite this