Quantifying the Cost of Shigella Diarrhea in the Enterics for Global Health (EFGH) Shigella Surveillance Study

Chloe Morozoff, Naveed Ahmed, Jobiba Chinkhumba, Md Taufiqul Islam, Abdoulie F. Jallow, Billy Ogwel, Loyda Fiorella Zegarra Paredes, Doh Sanogo, Hannah E. Atlas, Henry Badji, Naor Bar-Zeev, Bakary Conteh, Mario Güimack Fajardo, Erika Feutz, Fadima C. Haidara, Mehrab Karim, Adama Mamby Keita, Youssouf Keita, Farhana Khanam, Margaret N. KosekKaren L. Kotloff, Rebecca Maguire, Ishmail S. Mbutuka, Maureen Ndalama, John Benjamin Ochieng, Collins Okello, Richard Omore, Karin F. Perez Garcia, Farah Naz Qamar, Syed Qudrat-E-Khuda, Sonia Qureshi, Md Nazmul Hasan Rajib, Wagner Valentino Shapiama Lopez, Shazia Sultana, Desiree Witte, Mohammad Tahir Yousafzai, Alex O. Awuor, Nigel A. Cunliffe, M. Jahangir Hossain, Maribel Paredes Olortegui, Milagritos D. Tapia, K. Zaman, Arianna Rubin Means

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Background. Comparative costs of public health interventions provide valuable data for decision making. However, the availability of comprehensive and context-specific costs is often limited. The Enterics for Global Health (EFGH) Shigella surveillance study—a facility-based diarrhea surveillance study across 7 countries—aims to generate evidence on health system and household costs associated with medically attended Shigella diarrhea in children. Methods. EFGH working groups comprising representatives from each country (Bangladesh, Kenya, Malawi, Mali, Pakistan, Peru, and The Gambia) developed the study methods. Over a 24-month surveillance period, facility-based surveys will collect data on resource use for the medical treatment of an estimated 9800 children aged 6–35 months with diarrhea. Through these surveys, we will describe and quantify medical resources used in the treatment of diarrhea (eg, medication, supplies, and provider salaries), nonmedical resources (eg, travel costs to the facility), and the amount of caregiver time lost from work to care for their sick child. To assign costs to each identified resource, we will use a combination of caregiver interviews, national medical price lists, and databases from the World Health Organization and the International Labor Organization. Our primary outcome will be the estimated cost per inpatient and outpatient episode of medically attended Shigella diarrhea treatment across countries, levels of care, and illness severity. We will conduct sensitivity and scenario analysis to determine how unit costs vary across scenarios. Conclusions. Results from this study will contribute to the existing body of literature on diarrhea costing and inform future policy decisions related to investments in preventive strategies for Shigella.

Original languageEnglish
Pages (from-to)S41-S47
JournalOpen Forum Infectious Diseases
Issue numberSupplement_1
Publication statusPublished - 1 Mar 2024


  • cost
  • cost of illness
  • diarrhea
  • health economics
  • Shigella


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