Raised 17-hydroxyprogesterone levels in congenital adrenal hyperplasia

Sahar Iqbal; Aysha Habib Khan

Raised 17-hydroxyprogesterone levels in congenital adrenal hyperplasia

Sahar Iqbal, Aysha Habib Khan

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Congenital adrenal hyperplasia (CAH) refers to autosomal recessive diseases resulting from deficiency of enzymes involved in the production of cortisol by the adrenal glands. This study was designed to determine the frequency of suspected congenital adrenal hyperplasia patients by evaluating the laboratory data of blood 17-OHP. The study was conducted at Chemical Pathology Section of Department of Pathology at the Aga Khan University, Karachi. The basic demographic data of 2282 subjects was recorded, screened for blood 17-OHP levels from January 2007 to December 2010. A cutoff of ≥ 4 ng/ml was considered as suggestive of CAH. The results showed 17-OHP levels ≥ 4 ng/ml were found predominantly among infants (14.4%) and in females (18.2%).

Original language	English
Pages (from-to)	373-374
Number of pages	2
Journal	Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Volume	23
Issue number	5
Publication status	Published - May 2013
Externally published	Yes

Keywords

17-hydroxyprogesterone
Congenital adrenal hyperplasia
Cut off value

Cite this

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title = "Raised 17-hydroxyprogesterone levels in congenital adrenal hyperplasia",

abstract = "Congenital adrenal hyperplasia (CAH) refers to autosomal recessive diseases resulting from deficiency of enzymes involved in the production of cortisol by the adrenal glands. This study was designed to determine the frequency of suspected congenital adrenal hyperplasia patients by evaluating the laboratory data of blood 17-OHP. The study was conducted at Chemical Pathology Section of Department of Pathology at the Aga Khan University, Karachi. The basic demographic data of 2282 subjects was recorded, screened for blood 17-OHP levels from January 2007 to December 2010. A cutoff of ≥ 4 ng/ml was considered as suggestive of CAH. The results showed 17-OHP levels ≥ 4 ng/ml were found predominantly among infants (14.4%) and in females (18.2%).",

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AU - Khan, Aysha Habib

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N2 - Congenital adrenal hyperplasia (CAH) refers to autosomal recessive diseases resulting from deficiency of enzymes involved in the production of cortisol by the adrenal glands. This study was designed to determine the frequency of suspected congenital adrenal hyperplasia patients by evaluating the laboratory data of blood 17-OHP. The study was conducted at Chemical Pathology Section of Department of Pathology at the Aga Khan University, Karachi. The basic demographic data of 2282 subjects was recorded, screened for blood 17-OHP levels from January 2007 to December 2010. A cutoff of ≥ 4 ng/ml was considered as suggestive of CAH. The results showed 17-OHP levels ≥ 4 ng/ml were found predominantly among infants (14.4%) and in females (18.2%).

AB - Congenital adrenal hyperplasia (CAH) refers to autosomal recessive diseases resulting from deficiency of enzymes involved in the production of cortisol by the adrenal glands. This study was designed to determine the frequency of suspected congenital adrenal hyperplasia patients by evaluating the laboratory data of blood 17-OHP. The study was conducted at Chemical Pathology Section of Department of Pathology at the Aga Khan University, Karachi. The basic demographic data of 2282 subjects was recorded, screened for blood 17-OHP levels from January 2007 to December 2010. A cutoff of ≥ 4 ng/ml was considered as suggestive of CAH. The results showed 17-OHP levels ≥ 4 ng/ml were found predominantly among infants (14.4%) and in females (18.2%).

KW - 17-hydroxyprogesterone

KW - Congenital adrenal hyperplasia

KW - Cut off value

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SN - 1022-386X

VL - 23

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JO - Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

JF - Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

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ER -

Raised 17-hydroxyprogesterone levels in congenital adrenal hyperplasia

Abstract

Keywords

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