Reducing medication errors in critical care: A multimodal approach

Rachel M. Kruer, Andrew S. Jarrell, Asad Latif

Research output: Contribution to journalReview articlepeer-review

29 Citations (Scopus)


The Institute of Medicine has reported that medication errors are the single most common type of error in health care, representing 19% of all adverse events, while accounting for over 7,000 deaths annually. The frequency of medication errors in adult intensive care units can be as high as 947 per 1,000 patient-days, with a median of 105.9 per 1,000 patient-days. The formulation of drugs is a potential contributor to medication errors. Challenges related to drug formulation are specific to the various routes of medication administration, though errors associated with medication appearance and labeling occur among all drug formulations and routes of administration. Addressing these multifaceted challenges requires a multimodal approach. Changes in technology, training, systems, and safety culture are all strategies to potentially reduce medication errors related to drug formulation in the intensive care unit.

Original languageEnglish
Pages (from-to)117-126
Number of pages10
JournalClinical Pharmacology: Advances and Applications
Publication statusPublished - 1 Sept 2014
Externally publishedYes


  • Drug design
  • Drug formulation
  • Medication safety
  • Patient safety


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