Reference ranges of handgrip strength from 125,462 healthy adults in 21 countries: a prospective urban rural epidemiologic (PURE) study

Darryl P. Leong; Koon K. Teo; Sumathy Rangarajan; V. Raman Kutty; Fernando Lanas; Chen Hui; Xiang Quanyong; Qian Zhenzhen; Tang Jinhua; Ismail Noorhassim; Khalid F. AlHabib; Sarah J. Moss; Annika Rosengren; Ayse Arzu Akalin; Omar Rahman; Jephat Chifamba; Andrés Orlandini; Rajesh Kumar; Karen Yeates; Rajeev Gupta; Afzalhussein Yusufali; Antonio Dans; Álvaro Avezum; Patricio Lopez-Jaramillo; Paul Poirier; Hosein Heidari; Katarzyna Zatonska; Romaina Iqbal; Rasha Khatib; Salim Yusuf

doi:10.1002/jcsm.12112

Reference ranges of handgrip strength from 125,462 healthy adults in 21 countries: a prospective urban rural epidemiologic (PURE) study

Darryl P. Leong, Koon K. Teo, Sumathy Rangarajan, V. Raman Kutty, Fernando Lanas, Chen Hui, Xiang Quanyong, Qian Zhenzhen, Tang Jinhua, Ismail Noorhassim, Khalid F. AlHabib, Sarah J. Moss, Annika Rosengren, Ayse Arzu Akalin, Omar Rahman, Jephat Chifamba, Andrés Orlandini, Rajesh Kumar, Karen Yeates, Rajeev GuptaAfzalhussein Yusufali, Antonio Dans, Álvaro Avezum, Patricio Lopez-Jaramillo, Paul Poirier, Hosein Heidari, Katarzyna Zatonska, Romaina Iqbal, Rasha Khatib, Salim Yusuf

Department of Community Health Sciences, Medical College, Pakistan

Research output: Contribution to journal › Article › peer-review

198 Citations (Scopus)

Abstract

Background: The measurement of handgrip strength (HGS) has prognostic value with respect to all-cause mortality, cardiovascular mortality and cardiovascular disease, and is an important part of the evaluation of frailty. Published reference ranges for HGS are mostly derived from Caucasian populations in high-income countries. There is a paucity of information on normative HGS values in non-Caucasian populations from low- or middle-income countries. The objective of this study was to develop reference HGS ranges for healthy adults from a broad range of ethnicities and socioeconomically diverse geographic regions. Methods: HGS was measured using a Jamar dynamometer in 125,462 healthy adults aged 35-70 years from 21 countries in the Prospective Urban Rural Epidemiology (PURE) study. Results: HGS values differed among individuals from different geographic regions. HGS values were highest among those from Europe/North America, lowest among those from South Asia, South East Asia and Africa, and intermediate among those from China, South America, and the Middle East. Reference ranges stratified by geographic region, age, and sex are presented. These ranges varied from a median (25^th–75^th percentile) 50 kg (43–56 kg) in men <40 years from Europe/North America to 18 kg (14–20 kg) in women >60 years from South East Asia. Reference ranges by ethnicity and body-mass index are also reported. Conclusions: Individual HGS measurements should be interpreted using region/ethnic-specific reference ranges.

Original language	English
Pages (from-to)	535-546
Number of pages	12
Journal	Journal of Cachexia, Sarcopenia and Muscle
Volume	7
Issue number	5
DOIs	https://doi.org/10.1002/jcsm.12112
Publication status	Published - 1 Dec 2016

Keywords

handgrip strength
muscle strength
normative range
reference range
reference value

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/jcsm.12112

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Leong, D. P., Teo, K. K., Rangarajan, S., Kutty, V. R., Lanas, F., Hui, C., Quanyong, X., Zhenzhen, Q., Jinhua, T., Noorhassim, I., AlHabib, K. F., Moss, S. J., Rosengren, A., Akalin, A. A., Rahman, O., Chifamba, J., Orlandini, A., Kumar, R., Yeates, K., ... Yusuf, S. (2016). Reference ranges of handgrip strength from 125,462 healthy adults in 21 countries: a prospective urban rural epidemiologic (PURE) study. Journal of Cachexia, Sarcopenia and Muscle, 7(5), 535-546. https://doi.org/10.1002/jcsm.12112

@article{7e83267036d842bfb0d0167e32a4900b,

title = "Reference ranges of handgrip strength from 125,462 healthy adults in 21 countries: a prospective urban rural epidemiologic (PURE) study",

abstract = "Background: The measurement of handgrip strength (HGS) has prognostic value with respect to all-cause mortality, cardiovascular mortality and cardiovascular disease, and is an important part of the evaluation of frailty. Published reference ranges for HGS are mostly derived from Caucasian populations in high-income countries. There is a paucity of information on normative HGS values in non-Caucasian populations from low- or middle-income countries. The objective of this study was to develop reference HGS ranges for healthy adults from a broad range of ethnicities and socioeconomically diverse geographic regions. Methods: HGS was measured using a Jamar dynamometer in 125,462 healthy adults aged 35-70 years from 21 countries in the Prospective Urban Rural Epidemiology (PURE) study. Results: HGS values differed among individuals from different geographic regions. HGS values were highest among those from Europe/North America, lowest among those from South Asia, South East Asia and Africa, and intermediate among those from China, South America, and the Middle East. Reference ranges stratified by geographic region, age, and sex are presented. These ranges varied from a median (25th–75th percentile) 50 kg (43–56 kg) in men <40 years from Europe/North America to 18 kg (14–20 kg) in women >60 years from South East Asia. Reference ranges by ethnicity and body-mass index are also reported. Conclusions: Individual HGS measurements should be interpreted using region/ethnic-specific reference ranges.",

keywords = "handgrip strength, muscle strength, normative range, reference range, reference value",

author = "Leong, {Darryl P.} and Teo, {Koon K.} and Sumathy Rangarajan and Kutty, {V. Raman} and Fernando Lanas and Chen Hui and Xiang Quanyong and Qian Zhenzhen and Tang Jinhua and Ismail Noorhassim and AlHabib, {Khalid F.} and Moss, {Sarah J.} and Annika Rosengren and Akalin, {Ayse Arzu} and Omar Rahman and Jephat Chifamba and Andr{\'e}s Orlandini and Rajesh Kumar and Karen Yeates and Rajeev Gupta and Afzalhussein Yusufali and Antonio Dans and {\'A}lvaro Avezum and Patricio Lopez-Jaramillo and Paul Poirier and Hosein Heidari and Katarzyna Zatonska and Romaina Iqbal and Rasha Khatib and Salim Yusuf",

note = "Publisher Copyright: {\textcopyright} 2016 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of the Society of Sarcopenia, Cachexia and Wasting Disorders",

year = "2016",

month = dec,

day = "1",

doi = "10.1002/jcsm.12112",

language = "English",

volume = "7",

pages = "535--546",

journal = "Journal of Cachexia, Sarcopenia and Muscle",

issn = "2190-5991",

publisher = "Wiley-Blackwell",

number = "5",

}

Leong, DP, Teo, KK, Rangarajan, S, Kutty, VR, Lanas, F, Hui, C, Quanyong, X, Zhenzhen, Q, Jinhua, T, Noorhassim, I, AlHabib, KF, Moss, SJ, Rosengren, A, Akalin, AA, Rahman, O, Chifamba, J, Orlandini, A, Kumar, R, Yeates, K, Gupta, R, Yusufali, A, Dans, A, Avezum, Á, Lopez-Jaramillo, P, Poirier, P, Heidari, H, Zatonska, K, Iqbal, R, Khatib, R & Yusuf, S 2016, 'Reference ranges of handgrip strength from 125,462 healthy adults in 21 countries: a prospective urban rural epidemiologic (PURE) study', Journal of Cachexia, Sarcopenia and Muscle, vol. 7, no. 5, pp. 535-546. https://doi.org/10.1002/jcsm.12112

TY - JOUR

T1 - Reference ranges of handgrip strength from 125,462 healthy adults in 21 countries

T2 - a prospective urban rural epidemiologic (PURE) study

AU - Leong, Darryl P.

AU - Teo, Koon K.

AU - Rangarajan, Sumathy

AU - Kutty, V. Raman

AU - Lanas, Fernando

AU - Hui, Chen

AU - Quanyong, Xiang

AU - Zhenzhen, Qian

AU - Jinhua, Tang

AU - Noorhassim, Ismail

AU - AlHabib, Khalid F.

AU - Moss, Sarah J.

AU - Rosengren, Annika

AU - Akalin, Ayse Arzu

AU - Rahman, Omar

AU - Chifamba, Jephat

AU - Orlandini, Andrés

AU - Kumar, Rajesh

AU - Yeates, Karen

AU - Gupta, Rajeev

AU - Yusufali, Afzalhussein

AU - Dans, Antonio

AU - Avezum, Álvaro

AU - Lopez-Jaramillo, Patricio

AU - Poirier, Paul

AU - Heidari, Hosein

AU - Zatonska, Katarzyna

AU - Iqbal, Romaina

AU - Khatib, Rasha

AU - Yusuf, Salim

PY - 2016/12/1

Y1 - 2016/12/1

N2 - Background: The measurement of handgrip strength (HGS) has prognostic value with respect to all-cause mortality, cardiovascular mortality and cardiovascular disease, and is an important part of the evaluation of frailty. Published reference ranges for HGS are mostly derived from Caucasian populations in high-income countries. There is a paucity of information on normative HGS values in non-Caucasian populations from low- or middle-income countries. The objective of this study was to develop reference HGS ranges for healthy adults from a broad range of ethnicities and socioeconomically diverse geographic regions. Methods: HGS was measured using a Jamar dynamometer in 125,462 healthy adults aged 35-70 years from 21 countries in the Prospective Urban Rural Epidemiology (PURE) study. Results: HGS values differed among individuals from different geographic regions. HGS values were highest among those from Europe/North America, lowest among those from South Asia, South East Asia and Africa, and intermediate among those from China, South America, and the Middle East. Reference ranges stratified by geographic region, age, and sex are presented. These ranges varied from a median (25th–75th percentile) 50 kg (43–56 kg) in men <40 years from Europe/North America to 18 kg (14–20 kg) in women >60 years from South East Asia. Reference ranges by ethnicity and body-mass index are also reported. Conclusions: Individual HGS measurements should be interpreted using region/ethnic-specific reference ranges.

AB - Background: The measurement of handgrip strength (HGS) has prognostic value with respect to all-cause mortality, cardiovascular mortality and cardiovascular disease, and is an important part of the evaluation of frailty. Published reference ranges for HGS are mostly derived from Caucasian populations in high-income countries. There is a paucity of information on normative HGS values in non-Caucasian populations from low- or middle-income countries. The objective of this study was to develop reference HGS ranges for healthy adults from a broad range of ethnicities and socioeconomically diverse geographic regions. Methods: HGS was measured using a Jamar dynamometer in 125,462 healthy adults aged 35-70 years from 21 countries in the Prospective Urban Rural Epidemiology (PURE) study. Results: HGS values differed among individuals from different geographic regions. HGS values were highest among those from Europe/North America, lowest among those from South Asia, South East Asia and Africa, and intermediate among those from China, South America, and the Middle East. Reference ranges stratified by geographic region, age, and sex are presented. These ranges varied from a median (25th–75th percentile) 50 kg (43–56 kg) in men <40 years from Europe/North America to 18 kg (14–20 kg) in women >60 years from South East Asia. Reference ranges by ethnicity and body-mass index are also reported. Conclusions: Individual HGS measurements should be interpreted using region/ethnic-specific reference ranges.

KW - handgrip strength

KW - muscle strength

KW - normative range

KW - reference range

KW - reference value

UR - http://www.scopus.com/inward/record.url?scp=84963692261&partnerID=8YFLogxK

U2 - 10.1002/jcsm.12112

DO - 10.1002/jcsm.12112

M3 - Article

C2 - 27104109

AN - SCOPUS:84963692261

SN - 2190-5991

VL - 7

SP - 535

EP - 546

JO - Journal of Cachexia, Sarcopenia and Muscle

JF - Journal of Cachexia, Sarcopenia and Muscle

IS - 5

ER -

Reference ranges of handgrip strength from 125,462 healthy adults in 21 countries: a prospective urban rural epidemiologic (PURE) study

Abstract

Keywords

UN SDGs

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