TY - JOUR
T1 - Relationship of optic nerve sheath diameter and intracranial hypertension in patients with traumatic brain injury
AU - Al-Hassani, Ammar
AU - Strandvik, Gustav
AU - Abayazeed, Sheraz
AU - Ahmed, Khalid
AU - El-Menyar, Ayman
AU - Mahmood, Ismail
AU - Arumugam, Suresh Kumar
AU - Asim, Mohammad
AU - Nabir, Syed
AU - Ahmed, Nadeem
AU - Ahmed, Zahoor
AU - Al-Thani, Hassan
N1 - Publisher Copyright:
© 2020 Journal of Emergencies, Trauma, and Shock| Published by Wolters Kluwer - Medknow.
PY - 2020/7/1
Y1 - 2020/7/1
N2 - Background: to study the association between optic nerve sheath diameter (ONSD) and intracranial pressure (ICP) in patients with moderate-to-severe brain injury. Patients and Methods: A retrospective cohort study of traumatic brain injury (TBI) patients was conducted between 2010 and 2014. Data were analyzed and compared according to the ICP monitoring cutoff values. Outcomes included intracranial hypertension (ICH) and mortality. Results: A total of 167 patients with a mean age of 33 ± 14 years, of them 96 had ICP monitored. ICP values correlated with ONSD measurement (r = 0.21, P = 0.04). Patients who developed ICH were more likely to have higher mean ONSD (P = 0.01) and subarachnoid hemorrhage (SAH) (P = 0.004). Receiver operating curve for ONSD showed a cutoff value of 5.6 mm to detect ICH with sensitivity 72.2% and specificity 50%. Age and ICP were independent predictors of inhospital mortality in multivariate model. Another model with same covariates showed ONSD and SAH to be independent predictors of ICH. Simple linear regression showed a significant association of ONSD with increased ICP (β = 0.21, 95% confidence interval 0.25-5.08, P = 0.03). Conclusions: ONSD is a simple noninvasive measurement on initial CT in patients with TBI that could be a surrogate for ICP monitoring. However, further studies are warranted.
AB - Background: to study the association between optic nerve sheath diameter (ONSD) and intracranial pressure (ICP) in patients with moderate-to-severe brain injury. Patients and Methods: A retrospective cohort study of traumatic brain injury (TBI) patients was conducted between 2010 and 2014. Data were analyzed and compared according to the ICP monitoring cutoff values. Outcomes included intracranial hypertension (ICH) and mortality. Results: A total of 167 patients with a mean age of 33 ± 14 years, of them 96 had ICP monitored. ICP values correlated with ONSD measurement (r = 0.21, P = 0.04). Patients who developed ICH were more likely to have higher mean ONSD (P = 0.01) and subarachnoid hemorrhage (SAH) (P = 0.004). Receiver operating curve for ONSD showed a cutoff value of 5.6 mm to detect ICH with sensitivity 72.2% and specificity 50%. Age and ICP were independent predictors of inhospital mortality in multivariate model. Another model with same covariates showed ONSD and SAH to be independent predictors of ICH. Simple linear regression showed a significant association of ONSD with increased ICP (β = 0.21, 95% confidence interval 0.25-5.08, P = 0.03). Conclusions: ONSD is a simple noninvasive measurement on initial CT in patients with TBI that could be a surrogate for ICP monitoring. However, further studies are warranted.
KW - Computed tomography
KW - intracranial pressure
KW - optic nerve sheath diameter
KW - traumatic brain injury
UR - http://www.scopus.com/inward/record.url?scp=85093835486&partnerID=8YFLogxK
U2 - 10.4103/JETS.JETS_103_19
DO - 10.4103/JETS.JETS_103_19
M3 - Article
AN - SCOPUS:85093835486
SN - 0974-2700
VL - 13
SP - 183
EP - 189
JO - Journal of Emergencies, Trauma and Shock
JF - Journal of Emergencies, Trauma and Shock
IS - 3
ER -