Rhinocerebral mucormycosis: Therapy with amphotericin B lipid complex

Mark D. Strasser, Rebecca J. Kennedy, Rodney D. Adam

Research output: Contribution to journalArticlepeer-review

92 Citations (Scopus)

Abstract

Rhinocerebral mucormycosis with intracranial involvement has a high mortality. The standard therapy consists of aggressive surgical debridement accompanied by high doses of amphotericin B deoxycholate. Even with this therapy, the mortality rate has been 48% in the series reported since 1980. We treated a 60-year-old diabetic woman with rhinocerebral mucormycosis involving the cavernous sinus whose infection responded to medical therapy with amphotericin B lipid complex. To our knowledge, this is the only well- documented medical care of a patient with rhinocerebral mucormycosis and intracranial involvement.

Original languageEnglish
Pages (from-to)337-339
Number of pages3
JournalArchives of Internal Medicine
Volume156
Issue number3
DOIs
Publication statusPublished - 12 Feb 1996
Externally publishedYes

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