Risk assessment of malathion on health indicators of catfish: Food and water security prospective research

Z. Ahmad, H. F. Alkahem Al-Balawi, K. A. Al-Ghanim, F. Al-Misned, S. Mahboob

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Specimens of Heteropneustes fossilis were treated with various levels of malathion and its 96 h LC50 value was determined. The effects of sub-lethal concentrations of insecticide on hematological and biochemical profile of Heteropneustes fossilis were also registered. The 96 h LC50 value obtained was 8.81 mg/l. Exposure of sub-lethal doses (0.44, 0.88 and 1.76 mg/l which are 5, 10 and 20% of the LC50) of malathion to Heteropneustes fossilis for 3 weeks demonstrated that the toxicant had a detrimental effect on the blood profile of fish. Blood cell (Erythrocyte and leucocytes) counts (from 1.66 to 1.44 cell × 106 × mm3 and 37.93 to 30.24 cell × 103 × mm3; respectively), haemoglobin (Hb) level (from 6.21 to 3.54 g/dl) and haematocrit (Ht) estimates (from 34.26 to 30.52%) were reduced in the fishes exposed to malathion. Elevated level (from 46.25 to 92.45 mg/100 ml) of glucose and decreased quantity (29.95 to 24.25 g/dl) of protein in plasma was registered. Glycogen content in muscle and liver was also decreased. The activity of enzymes glutamic-oxaloacetic transaminase (GOT) and glutamic-pyruvic transaminase (GPT) were high in the fish treated with pesticide. The possible causes for variations in the different parameters were identified and discussed.

Original languageEnglish
Article number101294
JournalJournal of King Saud University - Science
Issue number2
Publication statusPublished - Mar 2021
Externally publishedYes


  • Acute toxicity
  • Blood cell count
  • Enzymes
  • Heteropneustes fossilis
  • Malathion
  • Sub-lethal treatment


Dive into the research topics of 'Risk assessment of malathion on health indicators of catfish: Food and water security prospective research'. Together they form a unique fingerprint.

Cite this