Role of N-acetyl-β-D-glucosaminidase in the diagnosis of arthopathies

N-Acetyl-β-D-glucosaminidase activity in plasma of patients with arthopathies is significantly higher as compared to its activity in plasma of normal healthy subjects. There appears to be an association between plasma N-acetyl-β-D-glucosaminidase value and the severity of the disease. Mean value of this enzyme in plasma of severe cases is significantly higher than mild and moderate cases of arthopathies. N-acetyl-β-D-glucosaminidase may be useful as a non-specific marker for the diagnosis of arthopathies, such as rheumatoid arthritis and osteoarthritis.