Role of surgery in multifocal glioblastoma

Syeda Kubra Kishwar Jafri; Syed Sarmad Bukhari; Muhammad Shahzad Shamim

doi:10.47391/JPMA.22-021

Role of surgery in multifocal glioblastoma

Syeda Kubra Kishwar Jafri, Syed Sarmad Bukhari, Muhammad Shahzad Shamim

Section of Neurosurgery, Department of Surgery, Medical College, Pakistan

Research output: Contribution to journal › Article › peer-review

Abstract

The management of multifocal glioblastomas is a point of constant discussion amongst neuro-oncologists. Best outcomes in glioblastoma management come from gross total resection (GTR) followed by concomitant radiation and chemotherapy (CCRT). Multifocal disease is resistant to GTR. Conventional management of these lesion is usually biopsy only followed by CCRT. Recent evidence has shown that there may be some benefit to attempting GTR of the largest lesion whenever safe to do so.

Original language	English
Pages (from-to)	576-578
Number of pages	3
Journal	Journal of the Pakistan Medical Association
Volume	72
Issue number	3
DOIs	https://doi.org/10.47391/JPMA.22-021
Publication status	Published - Mar 2022

Keywords

Glioblastoma multiforme
chemotherapy
multifocal
radiotherapy

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abstract = "The management of multifocal glioblastomas is a point of constant discussion amongst neuro-oncologists. Best outcomes in glioblastoma management come from gross total resection (GTR) followed by concomitant radiation and chemotherapy (CCRT). Multifocal disease is resistant to GTR. Conventional management of these lesion is usually biopsy only followed by CCRT. Recent evidence has shown that there may be some benefit to attempting GTR of the largest lesion whenever safe to do so.",

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Role of surgery in multifocal glioblastoma

Abstract

Keywords

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