Safe thrombolysis during pregnancy for recurrent acute ischaemic stroke due to concomitant isolated left ventricular non-compaction and bilateral foetal posterior communicating arteries

Fatimah Osman Juma, Leonard Mzee Ngunga, Wangari Waweru-Siika, Dilraj Singh Sokhi

Research output: Contribution to journalArticlepeer-review

Abstract

Isolated left ventricular non-compaction (ILVNC) is a rare congenital cardiomyo-pathy and is associated with arrhythmias, heart failure and thromboembolism including ischaemic stroke. Pregnancy is a relative contraindication to thrombolysis for acute ischae-mic stroke, although case reports suggest the treatment can be given in selected cases. We report a case of recurrent cryptogenic strokes in a 36-year-old female who was thrombolysed with good outcome at 37 weeks’ gestation and was eventually found to have ILVNC as the cause. She had a predilection to recurrent posterior circulatory strokes due to foetal posterior communicating arteries. To our knowledge this is the first case report of safe thrombolysis for acute ischaemic stroke in pregnancy caused by ILVNC.

Original languageEnglish
Pages (from-to)591-595
Number of pages5
JournalInternational Medical Case Reports Journal
Volume14
DOIs
Publication statusPublished - 2021

Keywords

  • Foetal posterior communicating artery
  • Ischaemic stroke
  • Left ventricular non-compaction
  • Stroke in pregnancy

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