TY - JOUR
T1 - Sarcoidosis presenting as vocal cord palsy
T2 - an unusual presentation and literature review
AU - Raja, Mohummad Hassan Raza
AU - Javed, Muhammad Abdullah
AU - Zubairi, Ali Bin Sarwar
N1 - Publisher Copyright:
© 2020 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology
PY - 2021/2
Y1 - 2021/2
N2 - We report the case of a 60-year-old woman, presenting with left vocal cord paralysis (VCP). Diagnostic evaluation revealed sarcoidosis to be the underlying pathology. Computed tomography (CT) scans exhibited enlarged subcarinal, pretracheal, and prevascular lymph nodes as the possible mechanism of left VCP through compression of the left recurrent laryngeal nerve. Initial treatment with oral prednisolone and azathioprine led to remission of symptoms; however, tapering of dosage led to relapse of cough without any signs of VCP. The dosage of prednisolone was further boosted, leading to complete remission. A review of literature reveals 20 cases have been reported to date, with all but one involving the left vocal cord. This is the first reported case, with a relapse of the disease without a relapse of VCP, indicating the rarity of sarcoidosis-associated VCP.
AB - We report the case of a 60-year-old woman, presenting with left vocal cord paralysis (VCP). Diagnostic evaluation revealed sarcoidosis to be the underlying pathology. Computed tomography (CT) scans exhibited enlarged subcarinal, pretracheal, and prevascular lymph nodes as the possible mechanism of left VCP through compression of the left recurrent laryngeal nerve. Initial treatment with oral prednisolone and azathioprine led to remission of symptoms; however, tapering of dosage led to relapse of cough without any signs of VCP. The dosage of prednisolone was further boosted, leading to complete remission. A review of literature reveals 20 cases have been reported to date, with all but one involving the left vocal cord. This is the first reported case, with a relapse of the disease without a relapse of VCP, indicating the rarity of sarcoidosis-associated VCP.
KW - Cough
KW - hoarseness of voice
KW - respiratory structure and function
KW - sarcoidosis
KW - vocal cord paralysis
UR - http://www.scopus.com/inward/record.url?scp=85100518360&partnerID=8YFLogxK
U2 - 10.1002/rcr2.705
DO - 10.1002/rcr2.705
M3 - Article
AN - SCOPUS:85100518360
SN - 2051-3380
VL - 9
JO - Respirology Case Reports
JF - Respirology Case Reports
IS - 2
M1 - e00705
ER -