Securing personal e-Healthcare information aims mainly at protecting the privacy and confidentiality of the individual who receives healthcare services that are delivered through e-Health. Advances in security technologies have so far not eliminated the challenge posed by the need to secure e-Healthcare information. The rate of privacy and confidentiality breaches continue to increase unabated. These breaches pose challenges to all domains that converge on the task of securing information and building trust in e-Healthcare information management. Only a holistic approach that positions itself at the point of convergence of the domains of law, organisational policy, professional ethics and IT security could offer the promise to mitigate, if not eliminate, the major challenges to securing e-Healthcare information.