TY - JOUR
T1 - Small vulnerable newborns—big potential for impact
AU - UNICEF–WHO Low Birthweight Estimates Group
AU - Ashorn, Per
AU - Ashorn, Ulla
AU - Muthiani, Yvonne
AU - Aboubaker, Samira
AU - Askari, Sufia
AU - Bahl, Rajiv
AU - Black, Robert E.
AU - Dalmiya, Nita
AU - Duggan, Christopher P.
AU - Hofmeyr, G. Justus
AU - Kennedy, Stephen H.
AU - Klein, Nigel
AU - Lawn, Joy E.
AU - Shiffman, Jeremy
AU - Simon, Jonathon
AU - Temmerman, Marleen
AU - Okwaraji, Yemisrach
AU - Krasevec, Julia
AU - Bradley, Ellen
AU - Conkle, Joel
AU - Stevens, Gretchen
AU - Gatica, Giovanna
AU - Ohuma, Eric O.
AU - Coffey, Chris
AU - Estevez Dominguez, Diana
AU - Blencowe, Hannah
AU - Kimathi, Ben
AU - Moller, Ann Beth
AU - Lewin, Alexandra
AU - Hussain-Alkhateeb, Laith
AU - Borghi, Elaine
AU - Hayashi, Chika
N1 - Publisher Copyright:
© 2023 Elsevier Ltd
PY - 2023/5/20
Y1 - 2023/5/20
N2 - Despite major achievements in child survival, the burden of neonatal mortality has remained high and even increased in some countries since 1990. Currently, most neonatal deaths are attributable to being born preterm, small for gestational age (SGA), or with low birthweight (LBW). Besides neonatal mortality, these conditions are associated with stillbirth and multiple morbidities, with short-term and long-term adverse consequences for the newborn, their families, and society, resulting in a major loss of human capital. Prevention of preterm birth, SGA, and LBW is thus critical for global child health and broader societal development. Progress has, however, been slow, largely because of the global community's failure to agree on the definition and magnitude of newborn vulnerability and best ways to address it, to frame the problem attractively, and to build a broad coalition of actors and a suitable governance structure to implement a change. We propose a new definition and a conceptual framework, bringing preterm birth, SGA, and LBW together under a broader umbrella term of the small vulnerable newborn (SVN). Adoption of the framework and the unified definition can facilitate improved problem definition and improved programming for SVN prevention. Interventions aiming at SVN prevention would result in a healthier start for live-born infants, while also reducing the number of stillbirths, improving maternal health, and contributing to a positive economic and social development in the society.
AB - Despite major achievements in child survival, the burden of neonatal mortality has remained high and even increased in some countries since 1990. Currently, most neonatal deaths are attributable to being born preterm, small for gestational age (SGA), or with low birthweight (LBW). Besides neonatal mortality, these conditions are associated with stillbirth and multiple morbidities, with short-term and long-term adverse consequences for the newborn, their families, and society, resulting in a major loss of human capital. Prevention of preterm birth, SGA, and LBW is thus critical for global child health and broader societal development. Progress has, however, been slow, largely because of the global community's failure to agree on the definition and magnitude of newborn vulnerability and best ways to address it, to frame the problem attractively, and to build a broad coalition of actors and a suitable governance structure to implement a change. We propose a new definition and a conceptual framework, bringing preterm birth, SGA, and LBW together under a broader umbrella term of the small vulnerable newborn (SVN). Adoption of the framework and the unified definition can facilitate improved problem definition and improved programming for SVN prevention. Interventions aiming at SVN prevention would result in a healthier start for live-born infants, while also reducing the number of stillbirths, improving maternal health, and contributing to a positive economic and social development in the society.
UR - http://www.scopus.com/inward/record.url?scp=85159479059&partnerID=8YFLogxK
U2 - 10.1016/S0140-6736(23)00354-9
DO - 10.1016/S0140-6736(23)00354-9
M3 - Review article
C2 - 37167991
AN - SCOPUS:85159479059
SN - 0140-6736
VL - 401
SP - 1692
EP - 1706
JO - The Lancet
JF - The Lancet
IS - 10389
ER -