Socio-emotional and adaptive behaviour in children treated for severe anaemia at Lira Regional Referral Hospital, Uganda: a prospective cohort study

Andrew Sentoogo Ssemataf, Robert Opoka, John Mbaziira Ssenkusu, Noeline Nakasujja, Chandy John, Paul Bangirana

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Background: Severe anaemia is a global public health challenge commonly associated with morbidity and mortality among children

Methods: We conducted a hospital based prospective cohort study among children 6—42 months who were treated for severe anaemia (n=171) at Lira Regional Referral Hospital, Uganda. Socio-emotional and adaptive behaviour were assessed 14 days post discharge using the Bayley Scales of Infant and Toddler Development, 3rd edition. Age-adjusted z-scores for each domain were calculated using scores from healthy community children (n=88) from the same environment for each age category. Multiple linear regression was used to compare z-scores in the socialemotional and adaptive behaviour scales between the two groups after adjusting for weight-for-age z-score, social economic status, mother’s education, father’s education and father’s employment on all the scales.

Results: Compared with healthy community controls, children with severe anaemia had poorer [adjusted mean scores (standard error)], socio-emotional [−0.29, (0.05) vs. 0.01, (0.08), P=0.002]; but not overall/ composite adaptive behaviour [−0.10, (0.05) vs. −0.01, (0.07), P=0.343]. Within the adaptive behaviour subscales, children with SA displayed signifcantly poorer scores on the community use [adjusted mean score (standard error)], [−0.63, (0.10) vs. −0.01, (0.13), P

Conclusion: This study suggests that severe anaemia in children

Original languageUndefined/Unknown
JournalPaediatrics and Child Health, East Africa
Publication statusPublished - 1 Dec 2020

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