Stress management in cyst-forming free-living protists: Programmed cell death and/or encystment

Naveed Ahmed Khan, Junaid Iqbal, Ruqaiyyah Siddiqui

Research output: Contribution to journalReview articlepeer-review

11 Citations (Scopus)

Abstract

In the face of harsh conditions and given a choice, a cell may (i) undergo programmed cell death, (ii) transform into a cancer cell, or (iii) enclose itself into a cyst form. In metazoans, the available evidence suggests that cellular machinery exists only to execute or avoid programmed cell death, while the ability to form a cyst was either lost or never developed. For cyst-forming free-living protists, here we pose the question whether the ability to encyst was gained at the expense of the programmed cell death or both functions coexist to counter unfavorable environmental conditions with mutually exclusive phenotypes.

Original languageEnglish
Article number437534
JournalBioMed Research International
Volume2015
DOIs
Publication statusPublished - 12 Jan 2015

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