188Rhenium-glucoheptonate: A radiopharmaceutical for intravascular radiation therapy

S. Pervez, A. Mushtaq, M. Arif, Z. H. Chohan

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


The preparation of 188Re-glucoheptonate (GH) is described using 188Re, which was obtained from an alumina based 188W/188Re generator. The dependence of the radiolabeling yields of 188Re-GH on reducing agent concentration, GH concentration, pH, temperature and incubation time was examined. In the case of optimum conditions the yield of 188Re-GH was ∼99%. The ITLC technique was employed to monitor the different species formed. A biodistribution study of 188Re-GH was carried out in rats and compared to the biological behavior of 99mTc-GH.

Original languageEnglish
Pages (from-to)293-296
Number of pages4
JournalJournal of Radioanalytical and Nuclear Chemistry
Issue number2
Publication statusPublished - 1 May 2003
Externally publishedYes


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