Superbugs causing ventilator associated pneumonia in a tertiary care hospital and the return of pre-antibiotic era!

S. Qureshi, C. Agrawal, M. Madan, A. Pandey, H. Chauhan

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

The rise in super bugs causing Ventilator-Associated Pneumonia (VAP) is a major cause of mortality and morbidity despite recent advances in management owing to the looming 'antibiotic apocalypse'. The aetiology and susceptibility pattern of the VAP isolates varies with patient population, type of intensive care unit (ICU) and is an urgent diagnostic challenge. The present study carried out for a period of one year in a tertiary care hospital, enrolled patients on mechanical ventilation (MV) for ≥48 hrs. Endotracheal aspirates (ETA) from suspected VAP patients were processed by semi quantitative method. Staphylococus aureus, members of Enterobacteriaceae were more common in early onset VAP (EOVAP), while Nonfermenting Gram negative bacilli (NFGNB) were significantly associated with late onset VAP (LOVAP). Most of the isolates were multi drug resistant (MDR) super bugs. With limited treatment options left for this crisis situation like the pre-antibiotic era; it is an alarm for rational antibiotic therapy usage and intensive education programs.

Original languageEnglish
Pages (from-to)286-289
Number of pages4
JournalIndian Journal of Medical Microbiology
Volume33
Issue number2
DOIs
Publication statusPublished - 1 Apr 2015
Externally publishedYes

Keywords

  • Endotracheal aspirate
  • non fermenting gram negative bacilli
  • superbugs
  • ventilator associated pneumonia

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