Supernumerary derivative (22) syndrome resulting from a maternal balanced translocation

B. Afroze, Lock Hock Ngu, A. Roziana, M. Aminah, A. Noor Shahizan

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Supernumerary derivative (22) syndrome is one of the rare genomic syndromes. It is characterised by severe mental retardation, microcephaly, failure to thrive, ear anomalies, preauricular tags or sinus, cleft palate or high arch palate, microganathia, renal anomalies, congenital cardiac defects and genital abnormalities in males. In 99 percent of the cases, one of the parents is a balanced carrier of a translocation between chromosome 11 and chromosome 22. We report the first known case, a female neonate, of supernumerary derivative (22) syndrome from Malaysia.

Original languageEnglish
Pages (from-to)e372-e374
JournalSingapore Medical Journal
Issue number12
Publication statusPublished - Dec 2008
Externally publishedYes


  • Emanuel syndrome
  • Supernumerary derivative (22) syndrome
  • T(11;22)
  • Trisomy 11
  • Trisomy 22


Dive into the research topics of 'Supernumerary derivative (22) syndrome resulting from a maternal balanced translocation'. Together they form a unique fingerprint.

Cite this