Takotsubo cardiomyopathy, or broken-heart syndrome

Salim S. Virani, A. Nasser Khan, Cesar E. Mendoza, Alexandre C. Ferreira, Eduardo De Marchena

Research output: Contribution to journalArticlepeer-review

74 Citations (Scopus)


Takotsubo cardiomyopathy mimics acute coronary syndrome and is accompanied by reversible left ventricular apical ballooning in the absence of angiographically significant coronary artery stenosis. In Japanese, "tako-tsubo" means "fishing pot for trapping octopus," and the left ventricle of a patient diagnosed with this condition resembles that shape. Takotsubo cardiomyopathy, which is transient and typically precipitated by acute emotional stress, is also known as "stress cardiomyopathy" or "broken-heart syndrome." Herein, we describe the clinical angiographic characteristics of 4 patients who exhibited this syndrome, and we review the existing literature and propose reasons to conduct prospective studies.

Original languageEnglish
Pages (from-to)76-79
Number of pages4
JournalTexas Heart Institute Journal
Issue number1
Publication statusPublished - 2007
Externally publishedYes


  • Cardiomyopathies/diagnosis/etiology/physiopathology
  • Catecholamines/ secretion
  • Chest pain/etiology
  • Coronary angiography
  • Coronary disease/ physiopathology
  • Echocardiography
  • Electrocardiography
  • Heart/physiopathology
  • Myocardial ischemia/diagnosis


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