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The future of diagnostics in Africa

  • Yenew Kebede
  • , Nqobile Ndlovu
  • , Susan Nabadda
  • , Charles Sawadogo
  • , Damian Fuller
  • , Madhukar Pai
  • , Aytenew Ashenafi
  • , Lara Vojnov
  • , Rigveda Kadam
  • , Ashley Kallarakal
  • , Ilesh Jani
  • , Angela Mushavi
  • , Fatim Jallow
  • , Sheick Oumar Coulibaly
  • , Solange Baptiste
  • , Peter Ehrenkrantz
  • , Chase Mertz
  • , Gagandeep Kang
  • , Smiljka De Lussigny
  • , Anisa Ghadrshenas
  • Kenneth Fleming, Kekeletso Kao, Jason Williams, Wayne Van Germet, Brian Kaiser, Renuka Gadde, William Rodriguez, Noah Fongwen, Anafi Mataka, Silver Mashate, Juliet Bryant, Pascale Ondoa, Osborne Otieno, Obert Kachuwaire, Lucy Maryogo-Robinson, Sherrie Staley, Neha Agarwal, Shiri Brodsky, Abha Patil, Miraf Mesfin, Ravi Anupindi, Sidharth Rupani, Mpaphi Mbulawa, Heidi Albert, Mikashmi Kohli, Nitika Pai, Marguerite Loembe, Alaine Nyaruhirira, Boghuma Titanji, Nahid Bhadelia, Daniel Desalegn, Derrick Mimbe, Edwin Ochieng, Mary Mataranyika, Leon Biscornet, Namwaka Mulenga, Yucheng Tsai, Robia Islam, Fona Williams, Julie Ndasi, Francine Ntoumi, Mohammed Lamorde, Adolfo Vubil, Thebora Sultane, Arnab Pal, Sophie Magnet, Paolo Maggiore, Robert Luo, Shahin Sayed, Sadia Shakoor, Grace Umutesi, Gonzalo Domingo, Joseph Bitilinyu-Bangoh, Amadou Dieye, Collins Otieno, Ludovic Tamadea, Gad Murenzi, Jane Carter, Francis Ocen, Ana Capri, Lee Schroeder, Michael Wilson, Emily Gerth-Guyette, Davy Nsamba, Ignatius Awinibuno, Kingsley Odiabara, Tapiwanashe Kujinga, Fifa Rahman, Zee Ndlovu, Devan Dumas, Ndeye Sambe, Yashika Bansal, Zhi Zhen Qin, Lluis Donoso-Bach, Rina Estelle, Sindisiwe Dlamini, Celestina Obiekea, Konrad Bradley, Trevor Peter

Research output: Contribution to journalArticlepeer-review

Abstract

Persistent gaps in access to quality diagnostic tests undermine progress toward improved health outcomes and resilience to disease outbreaks in Africa. Furthermore, resources for strengthening laboratory systems have faced growing constraints owing to recent reductions in official direct financial assistance, highlighting an urgent need to identify investments that are high impact and minimally donor reliant. In this Perspective, we present a set of priority systems strengthening interventions based on expected impact and feasibility. These include the need for efficient and integrated testing networks, the establishment and implementation of national essential diagnostic lists, modernized procurement and supply chain practices, improved digital health standards and targeted strengthening of testing infrastructure for epidemic-prone diseases. These initiatives should be customized to local contexts and supported by reliable financing, enhanced national leadership and management capacity and updated policies. We propose that collective action focused on these priorities will improve health outcomes and be cost-saving—and will be superior to existing, more fragmented efforts to close gaps in testing. This also provides a pathway to self-reliance in health security and universal healthcare in the Africa region.

Original languageEnglish (US)
JournalNature Medicine
DOIs
Publication statusAccepted/In press - 2026

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