The human squamous cervical carcinoma cell line, HOG‐1, is responsive to steroid hormones

J. O. White; R. N. Jones; J. D. Croxtall; R. P. Gleeson; T. Krausz; S. Pervez; A. Jamil; L. Guida; J. E. Beesley; W. P. Soutter

doi:10.1002/ijc.2910520216

The human squamous cervical carcinoma cell line, HOG‐1, is responsive to steroid hormones

J. O. White, R. N. Jones, J. D. Croxtall, R. P. Gleeson, T. Krausz, S. Pervez, A. Jamil, L. Guida, J. E. Beesley, W. P. Soutter

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Growth of the human squamous cervical carcinoma cell line, HOG‐1, was stimulated in response to oestradiol in serum‐containing and chemically defined medium. The oestradiol‐stimulated growth could be inhibited by 4‐OH tamoxifen, progesterone and medroxyprogesterone acetate; the last 2 compounds also inhibited basal cell growth in serum‐containing and chemically defined media. The data are consistent with the sensitivity of human squamous cervical cancer to sex‐steroid hormones and suggest that endocrine therapies may be of benefit in this disease. © 1992 Wiley‐Liss, Inc.

Original language	English
Pages (from-to)	247-251
Number of pages	5
Journal	International Journal of Cancer
Volume	52
Issue number	2
DOIs	https://doi.org/10.1002/ijc.2910520216
Publication status	Published - 9 Sept 1992
Externally published	Yes

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title = "The human squamous cervical carcinoma cell line, HOG‐1, is responsive to steroid hormones",

abstract = "Growth of the human squamous cervical carcinoma cell line, HOG‐1, was stimulated in response to oestradiol in serum‐containing and chemically defined medium. The oestradiol‐stimulated growth could be inhibited by 4‐OH tamoxifen, progesterone and medroxyprogesterone acetate; the last 2 compounds also inhibited basal cell growth in serum‐containing and chemically defined media. The data are consistent with the sensitivity of human squamous cervical cancer to sex‐steroid hormones and suggest that endocrine therapies may be of benefit in this disease. {\textcopyright} 1992 Wiley‐Liss, Inc.",

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doi = "10.1002/ijc.2910520216",

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T1 - The human squamous cervical carcinoma cell line, HOG‐1, is responsive to steroid hormones

AU - White, J. O.

AU - Jones, R. N.

AU - Croxtall, J. D.

AU - Gleeson, R. P.

AU - Krausz, T.

AU - Pervez, S.

AU - Jamil, A.

AU - Guida, L.

AU - Beesley, J. E.

AU - Soutter, W. P.

PY - 1992/9/9

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N2 - Growth of the human squamous cervical carcinoma cell line, HOG‐1, was stimulated in response to oestradiol in serum‐containing and chemically defined medium. The oestradiol‐stimulated growth could be inhibited by 4‐OH tamoxifen, progesterone and medroxyprogesterone acetate; the last 2 compounds also inhibited basal cell growth in serum‐containing and chemically defined media. The data are consistent with the sensitivity of human squamous cervical cancer to sex‐steroid hormones and suggest that endocrine therapies may be of benefit in this disease. © 1992 Wiley‐Liss, Inc.

AB - Growth of the human squamous cervical carcinoma cell line, HOG‐1, was stimulated in response to oestradiol in serum‐containing and chemically defined medium. The oestradiol‐stimulated growth could be inhibited by 4‐OH tamoxifen, progesterone and medroxyprogesterone acetate; the last 2 compounds also inhibited basal cell growth in serum‐containing and chemically defined media. The data are consistent with the sensitivity of human squamous cervical cancer to sex‐steroid hormones and suggest that endocrine therapies may be of benefit in this disease. © 1992 Wiley‐Liss, Inc.

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AN - SCOPUS:0026794408

SN - 0020-7136

VL - 52

SP - 247

EP - 251

JO - International Journal of Cancer

JF - International Journal of Cancer

IS - 2

ER -

The human squamous cervical carcinoma cell line, HOG‐1, is responsive to steroid hormones

Abstract

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