The predisposing pathology and clinical characteristics in the Scottish retinal detachment study

Danny Mitry, Jaswinder Singh, David Yorston, M. A.Rehman Siddiqui, Alan Wright, Brian W. Fleck, Harry Campbell, David G. Charteris

Research output: Contribution to journalArticlepeer-review

104 Citations (Scopus)

Abstract

Purpose: To describe the predisposing pathology and clinical features of all incident cases of rhegmatogenous retinal detachment (RRD) recruited in Scotland during a 2-year period. Design: Prospective surveillance study of incident cases of RRD. Participants: All incident cases of RRD recruited as part of the Scottish Retinal Detachment Study. Methods: During a 2-year period, we coordinated a comprehensive system in which every case of primary RRD presenting to 1 of 6 vitreoretinal surgical sites in Scotland was examined and approached for study inclusion. Main Outcome Measures: Rhegmatogenous retinal detachment incidence, predisposing features, and clinical characteristics. Results: A total of 1202 cases were recruited. Detailed clinical information was available on 1130 (94%) of cases. By causative break, the proportions of RRD were horseshoe tear (HST) associated with posterior vitreous detachment (PVD) in 86.2%, giant retinal tear (GRT) and PVD in 1.3%, non-PVD round hole (RH) in 4.9%, retinal dialysis in 5.9%, and retinoschisis RRD in 1.6%. One in 10 cases reported significant ocular trauma. One in 5 cases were pseudophakic. Round hole RRD more frequently presented with multiple retinal breaks compared with HST RRD (67.8% vs. 48.7%; P = 0.003). In PVD-associated RRD, 56.1% (95% confidence interval [CI], 53.858.3) of breaks were identified in the superotemporal retina. In non-PVD RRD, 54.6% (95% CI, 47.961.1) of breaks were inferotemporal, followed by superotemporal in 34.9% (95% CI, 28.741.5). Lattice degeneration was present in 18.7% of affected eyes and more common in RH RRD (35.7%) than in HST RRD (19.3%) (P = 0.003). Seven percent reported an affected first-degree relative, and these cases were significantly more myopic than nonfamilial cases. Conclusions: More than 85% of RRD cases are associated with PVD and related tractional tears. Non-PVD RH RRD occurred in younger and more myopic individuals. The majority of cases are caused by more than 1 retinal break, and the macula is affected in more than 50% at presentation. Ocular trauma, previous cataract surgery, family history, and lattice degeneration are important predisposing features. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.

Original languageEnglish
Pages (from-to)1429-1434
Number of pages6
JournalOphthalmology
Volume118
Issue number7
DOIs
Publication statusPublished - Jul 2011
Externally publishedYes

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