TY - JOUR
T1 - The preterm birth syndrome
T2 - Issues to consider in creating a classification system
AU - Goldenberg, Robert L.
AU - Gravett, Michael G.
AU - Iams, Jay
AU - Papageorghiou, Aris T.
AU - Waller, Sarah A.
AU - Kramer, Michael
AU - Culhane, Jennifer
AU - Barros, Fernando
AU - Conde-Agudelo, Augustin
AU - Bhutta, Zulfiqar A.
AU - Knight, Hannah E.
AU - Villar, Jose
N1 - Funding Information:
This project was supported by the Bill and Melinda Gates Foundation and the Global Alliance to Prevent Prematurity and Stillbirth, an initiative of Seattle Children's, and by INTERGROWTH-21st Grant ID 49038 from the Bill and Melinda Gates Foundation to the University of Oxford, for which we are very grateful.
PY - 2012/2
Y1 - 2012/2
N2 - A comprehensive classification system for preterm birth requires expanded gestational boundaries that recognize the early origins of preterm parturition and emphasize fetal maturity over fetal age. Exclusion of stillbirths, pregnancy terminations, and multifetal gestations prevents comprehensive consideration of the potential causes and presentations of preterm birth. Any step in parturition (cervical softening and ripening, decidual-membrane activation, and/or myometrial contractions) may initiate preterm parturition, and should be recorded for every preterm birth, as should the condition of the mother, fetus, newborn, and placenta, before a phenotype is assigned.
AB - A comprehensive classification system for preterm birth requires expanded gestational boundaries that recognize the early origins of preterm parturition and emphasize fetal maturity over fetal age. Exclusion of stillbirths, pregnancy terminations, and multifetal gestations prevents comprehensive consideration of the potential causes and presentations of preterm birth. Any step in parturition (cervical softening and ripening, decidual-membrane activation, and/or myometrial contractions) may initiate preterm parturition, and should be recorded for every preterm birth, as should the condition of the mother, fetus, newborn, and placenta, before a phenotype is assigned.
KW - classification
KW - phenotype
KW - preterm birth
UR - http://www.scopus.com/inward/record.url?scp=84856373530&partnerID=8YFLogxK
U2 - 10.1016/j.ajog.2011.10.865
DO - 10.1016/j.ajog.2011.10.865
M3 - Article
AN - SCOPUS:84856373530
SN - 0002-9378
VL - 206
SP - 113
EP - 118
JO - American Journal of Obstetrics and Gynecology
JF - American Journal of Obstetrics and Gynecology
IS - 2
ER -