To determine frequency of cervical intra-epithelial neoplasia and factors contributing to it, in high risk women attending gynae OPD of tertiary care hospital

Background: Gynecological carcinomas are among the most widely recognized malignancies in female. Cervical malignancy still keeps on being second commonest female cancer around the world. It represents for significant morbidity and mortality, every year there are roughly 1500 deaths in England and Wales from cancer of cervix. Cancer of cervix has pre-malignant condition called CIN (cervical intraepithelial neoplasia). CIN may advance to invasive carcinoma over time of 3-20 years in 70% patients. Aim: To determine frequency of cervical intraepithelial neoplasia and factors contributing to it, in high risk women attending Gynae OPD of tertiary care hospital. Methodology: It was a descriptive-cross sectional survey which included 400 cases which fulfill the inclusion and exclusion criteria. The study period was one year from July 2017 to July 2018 and was carried out in Obstetrics & Gynaecology Department, M. Islam Medical College, Gujranwala. Results: A total of 400 cases were enrolled, 112(28%) cases between 20-30 years, 134(33.5%) between 31-40, 89(22.25%) between 41-50 and only 65(16.25%) were between 51-60 years of age, mean age was 38.54+5.33 years, 89(22.25%) between 1-3 para, 248(62%) between 4-5 and only 63(15.75%) had >6 paras, frequency of cervical intraepithelial neoplasia reveals in 44(11%) out of them 19(43.18%) high parity, 17(38.64%) early marriage, 24(54.55%) had low socio economic status, 1(2.72%) had smoking history while 9(20.45%) were taking oral contraceptive pills were recorded as contributing factors of the morbidity. Conclusion: It is concluded that low socioeconomical status, higher parity and early marriage are the major contributing factors in diagnosed cases of cervical intraepithelial neoplasia, in women attending Gynae OPD of tertiary care hospital.