Total skin electron beam therapy (TSEBT) in management of mycosis fungoides: A case series

Sehrish Abrar, Bilal Mazhar Qureshi, Asim Hafiz, Nasir Ali, Agha Mohammad Hammad Khan, Ahmed Nadeem Abbasi

Research output: Contribution to journalArticlepeer-review


A retrospective review was conducted In Aga Khan University from January 2013-December 2020 for patients who received Total Skin Electron Beam Therapy (TSEBT) on the management of Mycosis Fungoides (MF). The clinical response rate and disease-free interval (DFI) was evaluated for three patients. All of the patients received a 3600 cGy dose of radiation. Clinical complete remission (cCR) was observed in two out of three patients, while one patient showed clinical partial response. Following the cCR to TSEBT, the DFI of the first patient with stage 1B lasted 30 months, while the second patient with stage IIB remained disease free for five months. TSEBT is an effective treatment for MF disease. It can thus be expected that patients with limited disease in the early stage can acquire a cCR with a longer DFI. The clinical outcomes of our study show concordance with the literature. The patients who had extensive (T3) skin involvement and had refractory diseases showed lower DFI with radiation.

Original languageEnglish
Pages (from-to)1208-1210
Number of pages3
JournalJournal of the Pakistan Medical Association
Issue number6
Publication statusPublished - Jun 2022


  • Clinical Response Rate
  • Disease-free interval
  • Modified Stanford technique
  • Mycosis Fungoides
  • Total skin electron beam therapy


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