TY - JOUR
T1 - Treatment of steroid-resistant focal segmental glomerulosclerosis with rituximab
T2 - A case report and review of literature
AU - Varwani, Mohamed Hasham
AU - Sokwala, Ahmed
PY - 2017/9/1
Y1 - 2017/9/1
N2 - Various immunomodulating agents have been tried for the treatment of steroid-resistant focal segmental glomerulosclerosis (FSGS) in the native kidney. A few case series and small studies have reported mixed results with the use of Rituximab for this indication. We report on the case of a 76-year-old male with steroid-resistant FSGS successfully treated with rituximab and remained in remission at the end of six months. A review of the literature highlights the paucity of data on this subject. We conclude that rituximab is a potentially useful treatment for steroid resistant FSGS and larger controlled studies are needed to further define its role in this setting.
AB - Various immunomodulating agents have been tried for the treatment of steroid-resistant focal segmental glomerulosclerosis (FSGS) in the native kidney. A few case series and small studies have reported mixed results with the use of Rituximab for this indication. We report on the case of a 76-year-old male with steroid-resistant FSGS successfully treated with rituximab and remained in remission at the end of six months. A review of the literature highlights the paucity of data on this subject. We conclude that rituximab is a potentially useful treatment for steroid resistant FSGS and larger controlled studies are needed to further define its role in this setting.
UR - https://www.scopus.com/pages/publications/85066843472
U2 - 10.4103/1319-2442.215133
DO - 10.4103/1319-2442.215133
M3 - Article
C2 - 28937082
AN - SCOPUS:85066843472
SN - 1319-2442
VL - 28
SP - 1175
EP - 1179
JO - Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.
JF - Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.
IS - 5
ER -