TY - JOUR
T1 - Trends in the burden and determinants of hypertensive heart disease in the Eastern Mediterranean region, 1990–2019
T2 - an analysis of the Global Burden of Disease Study 2019
AU - Mansouri, Asieh
AU - Khosravi, Alireza
AU - Mehrabani-Zeinabad, Kamran
AU - Kopec, Jacek A.
AU - Adawi, Karam I.I.
AU - Lui, Michelle
AU - Abdul Rahim, Hanan F.
AU - Anwar, Wagida
AU - Fadhil, Ibtihal
AU - Sulaiman, Kadhim
AU - Bazargani, Nooshin
AU - Saade, Georges
AU - Farhan, Hasan A.
AU - AlMahmeed, Wael
AU - Bokhari, Syedah Saira
AU - Hassen, Nejat
AU - Alandejani, Amani
AU - Shirani, Shahin
AU - Abdin, Amr
AU - Manla, Yosef
AU - Johnson, Catherine
AU - Stark, Benjamin
AU - Roth, Gregory A.
AU - Mokdad, Ali H.
AU - Shariful Islam, Sheikh Mohammed
AU - Sarrafzadegan, Nizal
N1 - Publisher Copyright:
© 2023 The Authors
PY - 2023/6
Y1 - 2023/6
N2 - Background: Hypertensive heart disease (HHD), one of the end-organ damage consequences of hypertension, is an important public health issue worldwide. Data on the HHD burden in the Eastern Mediterranean region (EMR) are scarce. We aimed to investigate the burden of HHD in the EMR, its member countries, and globally from 1990 to 2019. Methods: We used 2019 Global Burden of Disease (GBD) data to report the HHD age-standardised prevalence, disability adjusted life years (DALYs), years of life lost (YLLs), and mortality, as well as HHD risk factors attribution percent with their 95% uncertainty interval (UI). Global data are reported alongside EMR data, and its 22 respective countries. We compared the burden of HHD by socio-demographic index (SDI), sex, age groups, and countries. Findings: The age-standardised prevalence rate (per 100,000 population) of HHD was higher in the EMR (281.7; 95% UI: 204.5–383.4) in 2019, compared with the global prevalence (233.8; 95% UI: 170.5–312.9). The EMR age-standardised DALYs (per 100,000 population) for HHD in 2019 was 561.9 (361.0–704.1), compared with 268.2 (204.6–298.1) at the global level. There was an increase in HHD prevalence, reduction in mortality, and DALYs between 1990 and 2019 (4.01%, −7.6%, and −6.5%, respectively) in EMR. Among EMR countries, the highest versus lowest rates of age-standardised prevalence, mortality, and DALYs in 2019 [estimate (95% UI)] were in Jordan [561.62 (417.9–747.6)] versus Saudi Arabia [94.9 (69.5–129.0)]; Afghanistan [74.5 (23.7–112.3)] versus Saudi Arabia [4.3 (3.3–5.9)]; and Afghanistan [1374.1 (467.2–2020.7)] versus Qatar [87.11 (64.40–114.29)], respectively. Interpretation: HHD remains a significant problem in the EMR, with a higher burden than global levels. Serious efforts toward high-quality management and prevention are strongly recommended. Based on this study, our recommendation for the EMR is to adopt effective preventive strategies. For example, promoting healthy dietary patterns and prompt screening for undiagnosed HTN in public places, promoting regular blood pressure measurements at home, and creating community awareness about early detection of HTN. Funding: None.
AB - Background: Hypertensive heart disease (HHD), one of the end-organ damage consequences of hypertension, is an important public health issue worldwide. Data on the HHD burden in the Eastern Mediterranean region (EMR) are scarce. We aimed to investigate the burden of HHD in the EMR, its member countries, and globally from 1990 to 2019. Methods: We used 2019 Global Burden of Disease (GBD) data to report the HHD age-standardised prevalence, disability adjusted life years (DALYs), years of life lost (YLLs), and mortality, as well as HHD risk factors attribution percent with their 95% uncertainty interval (UI). Global data are reported alongside EMR data, and its 22 respective countries. We compared the burden of HHD by socio-demographic index (SDI), sex, age groups, and countries. Findings: The age-standardised prevalence rate (per 100,000 population) of HHD was higher in the EMR (281.7; 95% UI: 204.5–383.4) in 2019, compared with the global prevalence (233.8; 95% UI: 170.5–312.9). The EMR age-standardised DALYs (per 100,000 population) for HHD in 2019 was 561.9 (361.0–704.1), compared with 268.2 (204.6–298.1) at the global level. There was an increase in HHD prevalence, reduction in mortality, and DALYs between 1990 and 2019 (4.01%, −7.6%, and −6.5%, respectively) in EMR. Among EMR countries, the highest versus lowest rates of age-standardised prevalence, mortality, and DALYs in 2019 [estimate (95% UI)] were in Jordan [561.62 (417.9–747.6)] versus Saudi Arabia [94.9 (69.5–129.0)]; Afghanistan [74.5 (23.7–112.3)] versus Saudi Arabia [4.3 (3.3–5.9)]; and Afghanistan [1374.1 (467.2–2020.7)] versus Qatar [87.11 (64.40–114.29)], respectively. Interpretation: HHD remains a significant problem in the EMR, with a higher burden than global levels. Serious efforts toward high-quality management and prevention are strongly recommended. Based on this study, our recommendation for the EMR is to adopt effective preventive strategies. For example, promoting healthy dietary patterns and prompt screening for undiagnosed HTN in public places, promoting regular blood pressure measurements at home, and creating community awareness about early detection of HTN. Funding: None.
KW - Disability-adjusted life years
KW - Eastern Mediterranean region
KW - Global burden of disease
KW - Hypertensive heart disease
KW - Years of life lost
UR - http://www.scopus.com/inward/record.url?scp=85162234214&partnerID=8YFLogxK
U2 - 10.1016/j.eclinm.2023.102034
DO - 10.1016/j.eclinm.2023.102034
M3 - Article
AN - SCOPUS:85162234214
SN - 2589-5370
VL - 60
JO - eClinicalMedicine
JF - eClinicalMedicine
M1 - 102034
ER -
