Urinary tract infections in the infant

Mehreen Arshad, Patrick C. Seed

Research output: Contribution to journalReview articlepeer-review

80 Citations (Scopus)


Urinary tract infection (UTI) in an infant may be the first indication of an underlying renal disorder. Early recognition and initiation of adequate therapy for UTI is important to reduce the risk of long-term renal scarring. Ampicillin and gentamicin are traditionally the empiric treatment of choice; however, local antibiotic resistance patterns should be considered. Maternal antibiotics during pregnancy also increase the risk of resistant pathogens during neonatal UTI. Long-term management after the first UTI in infants remains controversial because of lack of specific studies in this age group and the risk-benefit issues for antibiotic prophylaxis between reduced recurrent disease and emergent antibiotic resistance.

Original languageEnglish
Pages (from-to)17-28
Number of pages12
JournalClinics in Perinatology
Issue number1
Publication statusPublished - 1 Mar 2015
Externally publishedYes


  • Antibiotic resistance
  • Escherichia coli
  • Infants
  • Renal imaging
  • Urinary tract infection
  • Vesicoureteral reflux


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