Varicella-Zoster Virus-Related: Cytomegalovirus (CMV) and Herpes Infections

Asma Akbar Ladak; Mohammad Wasay

doi:10.1017/9781108902793.024

Varicella-Zoster Virus-Related: Cytomegalovirus (CMV) and Herpes Infections

Asma Akbar Ladak
, Mohammad Wasay

Department of Medicine, Medical College, Pakistan

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

We present the case of a 36-year old male who presented with generalized tonic-clonic seizures and history of diffuse vesicular rash. In the ER, he was drowsy and disoriented with right hemiparesis. Investigations revealed IgG varicella antibodies in the CSF along with elevated homocysteine levels. MRV revealed extensive CVST in superficial sagittal sinus, right transverse sinus and superficial veins. He was treated with IV acyclovir, adequate hydration and was started on levetiracetam. He was put on low molecular weight heparin and continued on anticoagulation for 3 months. Follow up MRI showed recanalization of venous sinuses with no lesions. CVST secondary to VZV is a rare occurrence. We propose a diagnostic and treatment algorithm with our case.

Original language	English (US)
Title of host publication	Rare Causes of Stroke
Subtitle of host publication	A Handbook
Publisher	Cambridge University Press
Pages	137-140
Number of pages	4
ISBN (Electronic)	9781108902793
ISBN (Print)	9781108821254
DOIs	https://doi.org/10.1017/9781108902793.024
Publication status	Published - 1 Jan 2022

Keywords

Adequate hydration
Homocysteine
Skin lesions
Thrombotic complications
Varicella zoster meningoencephalitis

Access to Document

10.1017/9781108902793.024

Cite this

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abstract = "We present the case of a 36-year old male who presented with generalized tonic-clonic seizures and history of diffuse vesicular rash. In the ER, he was drowsy and disoriented with right hemiparesis. Investigations revealed IgG varicella antibodies in the CSF along with elevated homocysteine levels. MRV revealed extensive CVST in superficial sagittal sinus, right transverse sinus and superficial veins. He was treated with IV acyclovir, adequate hydration and was started on levetiracetam. He was put on low molecular weight heparin and continued on anticoagulation for 3 months. Follow up MRI showed recanalization of venous sinuses with no lesions. CVST secondary to VZV is a rare occurrence. We propose a diagnostic and treatment algorithm with our case.",

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T1 - Varicella-Zoster Virus-Related

T2 - Cytomegalovirus (CMV) and Herpes Infections

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AU - Wasay, Mohammad

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N2 - We present the case of a 36-year old male who presented with generalized tonic-clonic seizures and history of diffuse vesicular rash. In the ER, he was drowsy and disoriented with right hemiparesis. Investigations revealed IgG varicella antibodies in the CSF along with elevated homocysteine levels. MRV revealed extensive CVST in superficial sagittal sinus, right transverse sinus and superficial veins. He was treated with IV acyclovir, adequate hydration and was started on levetiracetam. He was put on low molecular weight heparin and continued on anticoagulation for 3 months. Follow up MRI showed recanalization of venous sinuses with no lesions. CVST secondary to VZV is a rare occurrence. We propose a diagnostic and treatment algorithm with our case.

AB - We present the case of a 36-year old male who presented with generalized tonic-clonic seizures and history of diffuse vesicular rash. In the ER, he was drowsy and disoriented with right hemiparesis. Investigations revealed IgG varicella antibodies in the CSF along with elevated homocysteine levels. MRV revealed extensive CVST in superficial sagittal sinus, right transverse sinus and superficial veins. He was treated with IV acyclovir, adequate hydration and was started on levetiracetam. He was put on low molecular weight heparin and continued on anticoagulation for 3 months. Follow up MRI showed recanalization of venous sinuses with no lesions. CVST secondary to VZV is a rare occurrence. We propose a diagnostic and treatment algorithm with our case.

KW - Adequate hydration

KW - Homocysteine

KW - Skin lesions

KW - Thrombotic complications

KW - Varicella zoster meningoencephalitis

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M3 - Chapter

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EP - 140

BT - Rare Causes of Stroke

PB - Cambridge University Press

ER -

Varicella-Zoster Virus-Related: Cytomegalovirus (CMV) and Herpes Infections

Abstract

Keywords

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