Vitamin D deficiency rickets in breast‐fed infants presenting with hypocalcaemic seizures

I. Ahmed, M. Atiq, J. Iqbal, M. Khurshid, P. Whittaker

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67 Citations (Scopus)

Abstract

At the Aga Khan Hospital (AKUH), 65 infants presented with hypocalcaemic seizures, subsequently found to have rickets. Forty‐six infants less than 6 months were totally or predominantly breast fed. In a subgroup of 15 mothers and their infants, we found very low plasma levels of 25(OH) vitamin D of < 5 /ig/1 and 7.53.3$uMg/l, respectively. Neither mothers nor infants received vitamin D supplementation. Maternal vitamin D deficiency and non‐supplementation in the infants were the likely causes of rickets in our patients. Prophylactic vitamin D 400 i.u. administered to infants up to 2 years and 800 i.u. to women in pregnancy and during lactation is recommended to prevent vitamin D deficiency.

Original languageEnglish
Pages (from-to)941-942
Number of pages2
JournalActa Paediatrica, International Journal of Paediatrics
Volume84
Issue number8
DOIs
Publication statusPublished - Aug 1995
Externally publishedYes

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