Abstract
Waldenstrom's macroglobulinemia (WM) is a rare condition, accounting for approximately 2% of haematologic malignancies. The most common causes of death in these patients are progression of the malignant lymphoproliferative process, infection and cardiac failure. Acute leukemia is a rare event in the clinical course of WM. A number of case reports have documented the development of terminal acute leukemia in patients with WM following prolonged chemotherapy. We describe a case of an elderly man who was a diagnosed case of WM and treated with chlorambucil and cyclophosphamide. Four years later, he developed acute leukemia.
Original language | English |
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Pages (from-to) | 291 |
Number of pages | 1 |
Journal | Journal of the Pakistan Medical Association |
Volume | 56 |
Issue number | 6 |
Publication status | Published - Jun 2006 |